741606-27-9

Basic information

• Product Name: 1-[2-hydroxy-3-(4-octylphenoxy)propyl]indole-5-carbonitrile
• Synonyms: 1-[2-hydroxy-3-(4-octylphenoxy)propyl]indole-5-carbonitrile
• CAS NO: 741606-27-9
• Molecular Weight: 404.552
• Mol File: 741606-27-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-[2-hydroxy-3-(4-octylphenoxy)propyl]indole-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-hydroxy-3-(4-octylphenoxy)propyl]indole-5-carbonitrile(741606-27-9)
• EPA Substance Registry System: 1-[2-hydroxy-3-(4-octylphenoxy)propyl]indole-5-carbonitrile(741606-27-9)

Safety Data

• Hazardous Substances Data: 741606-27-9(Hazardous Substances Data)

Upstream product

• 15861-24-2 1H-indole-5-carbonitrile 
• 4223-17-0 2-[(4-octylphenoxy)methyl]oxirane 
• 1806-26-4 p-Octylphenol 
• 741606-45-1 1-oxiranylmethylindole-5-carbonitrile 

Downstream Products

• 935764-10-6 3-{1-[2-hydroxy-3-(4-octylphenoxy)propyl]indol-5-yl}-4,5-dihydro-1,2,4-oxadiazol-5-one 
• 741606-44-0 1-[2-hydroxy-3-(4-octylphenoxy)propyl]indole-5-carboxamide 

Relevant articles and documents

1-(5-Carboxy- and 5-carbamoylindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2α: Bioisosteric replacement of the carboxylic acid and carboxamide moiety

Indole-5-carboxylic acids and -carboxamides with 3-aryloxy-2-oxopropyl residues in position 1 were previously reported to be potent inhibitors of cytosolic phospholipase A2α (cPLA2α) isolated from human platelets. In continuation of

NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVES AS INHIBITORS OF PHOSPHOLIPASE A2

The invention relates to novel heteroaryl-substituted acetone derivatives, which inhibit the enzyme phospholipase A2, to pharmaceutical agents that contain said compounds and to a method for producing said compounds.