74163-11-4Relevant academic research and scientific papers
Anti-allergy activity of 10-oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acids
Schwender,Sunday,Kerbleski,Herzig
, p. 964 - 966 (1980)
A series of substituted 10-oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acids was prepared and evaluated as anti-allergy agents. The 8-chloro and unsubstituted analogues were more potent than cromolyn sodium and doxantrazole intravenously in the rat PCA test. None of the analogues possessed significant oral activity.
Substituted 10-oxo-10H-pyridazino(6,1-b)quinazoline-2-carboxylic acids
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, (2008/06/13)
The invention relates to substituted 10-oxo-10H-pyridazino(6,1-b)quinazoline-2-carboxylic acids having the formula: STR1 wherein R1 is hydrogen, halogen; R2 is hydrogen, lower alkyl containing one to three carbon atoms, or wherein R1 and R2 taken together with the carbon atoms to which they are attached in a benzo ring, and the pharmaceutically acceptable salts thereof. These compounds are useful as anti-allergic agents.
