Journal of Medicinal Chemistry p. 964 - 966 (1980)
Update date:2022-08-30
Topics:
Schwender
Sunday
Kerbleski
Herzig
A series of substituted 10-oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acids was prepared and evaluated as anti-allergy agents. The 8-chloro and unsubstituted analogues were more potent than cromolyn sodium and doxantrazole intravenously in the rat PCA test. None of the analogues possessed significant oral activity.
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(2020)