741677-29-2Relevant academic research and scientific papers
3-trifluoromethanesulfonamido-Pyrrolidine: A general organocatalyst for antf-selective mannich reactions
Pouliquen, Mickael,Blanchet, Jerome,Lasne, Marie-Claire,Rouden, Jacques
supporting information; experimental part, p. 1029 - 1032 (2009/04/07)
Mannich-type reactions of a glyoxylate imine with carbonyl compounds catalyzed by 3-trifluoromethanesulfonamidopyrrolidine proceed with high yields and anfi-stereoselectivity. The catalyst is easily prepared and the transformation appears to be quite general accommodating aldehydes or ketones.
Asymmetric synthesis of quaternary α-and β-amino acids and β-lactams via proline-catalyzed Mannich reactions with branched aldehyde donors
Chowdari, Naidu S.,Suri, Jeff T.,Barbas III, Carlos F.
, p. 2507 - 2510 (2007/10/03)
(Matrix Presented) L-Proline-catalyzed direct asymmetric Mannich reactions of N-PMP protected α-imino ethyl glyoxylate with various α,α-disubstituted aldehydes affords quaternary β-formyl α-amino acid derivatives with excellent yields and enantioselectivi
