115276-75-0

Basic information

• Product Name: Acetic acid, [(4-methoxyphenyl)imino]-, ethyl ester
• CAS NO: 115276-75-0
• Molecular Formula: C11H13NO3
• Molecular Weight: 207.229
• Mol File: 115276-75-0.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(4-methoxyphenyl)imino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(4-methoxyphenyl)imino]-, ethyl ester(115276-75-0)
• EPA Substance Registry System: Acetic acid, [(4-methoxyphenyl)imino]-, ethyl ester(115276-75-0)

Safety Data

• Hazardous Substances Data: 115276-75-0(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 64805-08-9 ethyl glyoxylate hydrate 
• 924-44-7 glyoxylic acid ethyl ester 
• 90-04-0 2-methoxy-phenylamine 
• 50845-77-7 N-(4-methoxy)phenylglycine ethyl ester 
• 617-37-8 oxalic acid monoethyl ester 

Downstream Products

• 690224-49-8 (S)-N-p-Methoxyphenyl-4-oxo-1,2,3,4-tetrahydro-pyridine-2-carboxylic acid ethyl ester 
• 409093-03-4 (2S,3S)-ethyl 3-formyl-2-[(4-methoxyphenyl)amino]octanoate 
• 627875-25-6 (2S,3S,E)-ethyl 3-formyl-2-(4-methoxyphenylamino)undec-5-enoate 

Relevant articles and documents

One-step synthesis of ethyl quinaldates by lewis acid catalyzed three-component coupling reaction of aromatic amines, aliphatic aldehydes and ethyl glyoxylate

A convenient, efficient and simple one-pot method for the synthesis of quinaldates was developed by three-component coupling reaction of an arylamine (1), ethyl glyoxylate and an aliphatic aldehyde (2) in the presence of Lewis acid catalyst. The reaction

Catalysis of highly stereoselective Mannich-type reactions of ketones with ?±-imino esters by a pyrrolidine-sulfonamide. Synthesis of unnatural α-amino acids

The novel pyrrolidine-sulfonamide I has been prepared and used successfully to catalyze Mannich-type reactions between ketones and α-imino esters. The process is used to efficiently synthesize functionalized α-amino acid derivatives with excellent levels

Chiral bifunctional organocatalysts in asymmetric aza-Morita-Baylis-Hillman reactions of ethyl (arylimino)acetates with methyl vinyl ketone and ethyl vinyl ketone

(Chemical Equation Presented) The bifunctional chiral phosphine Lewis base (R)-2′-diphenylphosphino-[1,1′-binaphthalene]-2-ol is an effective organocatalyst in the asymmetric aza-MBH reaction of ethyl (arylimino)acetates 1 with MVK and EVK to give the cor

Asymmetric synthesis of piperidines using the nitro-Mannich reaction☆

A method for the synthesis of functionalized piperidines containing 3 contiguous stereocentres in the 2-,3- and 4- positions uses a diastereoselective nitro-Mannich to control stereochemistry. The nitro-Mannich reaction between a β-aryl/heteroaryl substituted nitroalkanes and glyoxylate imine provides β-nitro-amines with good selectivity (70:30 to >95:5) for the syn, anti-diastereoisomers. Reductive cyclisation with BF3.OEt2 and Et3SiH gave, after purification, stereochemically pure piperidines in 19–57% yield for ten examples with different 4-aryl/heteroaryl substituents.

A convenient method for preparation of α-imino carboxylic acid derivatives and application to the asymmetric synthesis of unnatural α-amino acid derivative

We describe herein a manganese(IV) oxide-mediated oxidation of N-p-methoxyphenyl (PMP)-protected glycine derivatives for the synthesis of α-imino carboxylic acid derivatives. Using this methodology, utilization of unstable glyoxic acid derivatives was avo