741709-62-6

Basic information

• Product Name: 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER
• Synonyms: 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarbonitrile;2-Cyano-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-Cyanopyridine-4-boronic acid, pinacol ester 95%;4-(4,4,5,5-TetraMethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-2-carbonitrile;2-Pyridinecarbonitrile,4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile;2-cyanopyridin-4-ylboronic acid pinacol ester
• CAS NO: 741709-62-6
• Molecular Formula: C₁₂H₁₅BN₂O₂
• Molecular Weight: 230.08
• Product Categories: Amines;Boron Derivatives;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 741709-62-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 60-61℃
• Boiling Point: 366℃
• Flash Point: 175℃
• Appearance: /
• Density: 1.10
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -1.16±0.10(Predicted)
• CAS DataBase Reference: 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER(741709-62-6)
• EPA Substance Registry System: 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER(741709-62-6)

Safety Data

• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 741709-62-6(Hazardous Substances Data)

Usage

Uses

A pyridylborane derivative evaluated for its kinase inhibitory activity.

Upstream product

• 62150-45-2 4-bromo-2-cyanopyridine 
• 73183-34-3 bis(pinacol)diborane 
• 19235-89-3 4-chloro-pyridine-2-carbonitrile 

Downstream Products

• 1426699-21-9 4-{3-[1-(4-amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl]-5-chloro-2-methoxy-6-methylphenyl}pyridine-2-carbonitrile 
• 1560796-16-8 4-(2-(3,5-dimethoxyphenylethyl)-5-(phenylsulfonyl)-5H-pyrrolo[2,3-b]pyrazin-6-yl)picolinonitrile 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present disclosure features compounds useful for the treatment of BAF complex-related disorders.

SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS

The invention is concerned with the compounds of formula I or II: and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I or II as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.