741721-49-3Relevant academic research and scientific papers
RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF
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Page/Page column 40, (2011/04/14)
Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula (I) and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment
IMDIZO [4. 5-B] PYRIDINE DERIVATIVES USED AS RAF INHIBITORS
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Page/Page column 48, (2009/10/22)
Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
N- (6-AMINOPYRIDIN-3-YL) -3- (SULFONAMIDO) BENZAMIDE DERIVATIVES AS B-RAF INHIBITORS FOR THE TREATMENT OF CANCER
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Page/Page column 48, (2009/10/22)
Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
PYRAZOLE [3, 4-B] PYRIDINE RAF INHIBITORS
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Page/Page column 75, (2009/10/22)
Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
Synthesis and structure-activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents
Vara Prasad,Boyer, Frederick E.,Chupak, Lou,Dermyer, Michael,Ding, Qizhu,Gavardinas,Hagen, Susan E.,Huband, Michael D.,Jiao, Wenhua,Kaneko, Takushi,Maiti, Samarendra N.,Melnick, Michael,Romero, Karina,Patterson,Wu, Xiujuan
, p. 5392 - 5397 (2007/10/03)
We describe a novel class of benzocycloheptanone derived oxazolidinone antibacterial agents. The synthesis and antibacterial activities with structure variation is discussed.
ANTIBACTERIAL AGENTS
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Page 134, (2010/02/08)
Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications including use as antibacterial agents.
