74173-88-9

Upstream product

• 1336-21-6 ammonium hydroxide 
• 74173-87-8 2-amino-5-chloro-α-(2-fluorophenyl)benzenemethanol 
• 784-38-3 2-amino-5-chloro-2'-fluorobenzophenone 

Downstream Products

• 74173-89-0 4-Chloro-2[(2-fluorophenyl)methyl]-N-(1-aminoethylidene)benzenamine 

Relevant academic research and scientific papers

The studies of the intramolecular C-F---H-N hydrogen bonding using covalently-linked base pair models of F and A

Both 1H NMR and X-ray studies revealed that C-F---H-N intramolecular hydrogen bonding is not observed even in covalently-linked base pair models of F and A. These results strongly support the Kool's hypothesis.

2-[[2-Methyl-1-[2-benzoyl(or benzyl)phenyl]-1H-imidazol-5-yl]methyl]-1H-isoindole-1,3(2H)-diones

A multistep process is presented for the preparation of imidazobenzodiazepines of the formula STR1 wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl. Also presented are novel intermediates utilized in the process. The end products are useful as sedatives, anxiolytics, muscle relaxants and anticonvulsants. The end products are especially useful in intravenous compositions for use in preoperative anesthesia.