74182-38-0Relevant articles and documents
Multiaction Pt(IV) Carbamate Complexes Can Codeliver Pt(II) Drugs and Amine Containing Bioactive Molecules
Babu, Tomer,Gibson, Dan,Karmakar, Subhendu,Sarkar, Amrita,Schmidt, Claudia
, (2020/04/08)
Multiaction Pt(IV) prodrugs can overcome resistance associated with the FDA approved Pt(II) drugs like cisplatin. Intracellular reduction of the octahedral Pt(IV) derivatives of cisplatin releases cisplatin and the two axial ligands. When the released axi
Towards small molecule inhibitors of mono-ADP-ribosyltransferases
Ekblad, Torun,Lindgren, Anders E.G.,Andersson, C. David,Caraballo, Rémi,Thorsell, Ann-Gerd,Karlberg, Tobias,Spjut, Sara,Linusson, Anna,Schüler, Herwig,Elofsson, Mikael
supporting information, p. 546 - 551 (2015/04/14)
Protein ADP-ribosylation is a post-translational modification involved in DNA repair, protein degradation, transcription regulation, and epigenetic events. Intracellular ADP-ribosylation is catalyzed predominantly by ADP-ribosyltransferases with diphtheri
