74201-13-1

Usage

Uses

Used in Pharmaceutical Industry:
N-(2-Hydroxy-1,1-dimethylethyl)-2-methoxybenzenecarboxamide is used as an active pharmaceutical ingredient for its anti-inflammatory and analgesic properties, contributing to the development of medications and topical creams that address pain and inflammation.
Used in Treatment of Inflammatory Disorders:
In the medical field, N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE is utilized as a therapeutic agent for conditions such as arthritis, muscle pain, and other inflammatory disorders, owing to its capacity to alleviate symptoms associated with these health issues.
While the provided materials do not specify different applications across various industries, the primary uses highlighted are within the pharmaceutical and medical sectors, focusing on the compound's role in formulating medications and treating inflammatory conditions.

InChI:InChI=1/C12H17NO3/c1-12(2,8-14)13-11(15)9-6-4-5-7-10(9)16-3/h4-7,14H,8H2,1-3H3,(H,13,15)

Upstream product

• 579-75-9 2-Methoxybenzoic acid 

Downstream Products

• 57598-33-1 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 114799-75-6 EXP 8623 
• 114799-17-6 2-butyl-1-<(2'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole-5-carboxamide 
• 114798-27-5 2-butyl-4-chloro-5-hydroxymethyl-1-[(2'carboxybiphenyl-4-yl)methyl]imidazole 
• 128764-54-5 5-<<4-<<3-(N-isopropylamino)-2-hydroxypropyl>oxy>indole-2-carboxamido>methyl>-2-butyl-1-<(2'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole 
• 128764-55-6 5-<<4-<<3--2-hydroxypropyl>oxy>indole-2-carboxamido>methyl>-2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloroimidazole 
• 128764-56-7 5-<<4-<<3-(N-isopropylamino)-2-hydroxypropyl>oxy>indole-2-carboxamido>methyl>-2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloroimidazole 
• 114772-71-3 2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloro-5-(chloromethyl)imidazole hydrochloride 
• 133910-00-6 2-n-Butyl-4-chloro-1-[(2'-(2-triphenylmethyl-2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-imidazole-5-carboxaldehyde 
• 124750-09-0 1-<(2'-carboxylbiphenyl-4-yl)methyl>-5-(hydroxymethyl)-4-methyl-2-propylimidazole hydrochloride 
• 124750-13-6 2-butyl-4-chloro-1-<<2'-(1H-tetrazol-5-yl)biphenyl-4-yl>methyl>imidazole-5-carboxaldehyde benzenesulfonylhydrazone 
• 114772-63-3 1-<<2'-(tert-butoxycarbonyl)biphenyl-4-yl>methyl>-2-butyl-5-<<(2-methoxyethoxy)methoxy>methyl>-4-(trifluoromethyl)imidazole 
• 133909-99-6 2-n-butyl-4-chloro-1-[(2'-(2-triphenylmethyl-2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-imidazole-5-methanol 
• 124750-41-0 2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloro-5-<<<(1-naphthylamino)carbonyl>amino>methyl>imidazole 

Relevant academic research and scientific papers

Palladium-catalyzed electrophilic C–H fluorination of arenes using oxazoline as a removable directing group

Dimethyloxazoline was rationally designed to act as a removable ortho-directing group (DG) for the palladium-catalyzed C–H electrophilic fluorination of arenes. Using NFSI as the fluorinating agent, and Pd(II), Ag(I) catalytic system, electrophilic C(sp2–H) ortho-fluorination took place on a variety of aryl substrates to afford the corresponding mono- and di-fluorinated products.

Nonpeptide Angiotensin II Receptor Antagonists: The Discovery of a Series of N-(Biphenylylmethyl)imidazoles as Potent, Orally Active Antihypertensives

A new series of nonpeptide angiotensin II (AII) receptor antagonists has been prepared.These N-(biphenylylmethyl)imidazoles, e.g. 2-butyl-1--4-chloro-5-(hydroxymethyl)imidazole, differ from the previously reported N-(benzamidobenzyl)imidazoles and related compounds in that they produce a potent antihypertensive effect upon oral administration; the earlier series generally were active only when administered intravenously.It has been found that the acidic group at the 2'-position of the biphenyl is essential.Only ortho-substituted acids possess both high affinity for the AII receptor and good oral antihypertensive potency.The carboxylic acid group has been replaced with a variety of acidic isosteres, and the tetrazole ring has been found to be the most effective.The tetrazole derivative, DuP 753, is currently in development for the treatment of hypertension.