74201-13-1

Basic information

• Product Name: N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE
• Synonyms: N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE;6J-910;Bionet2_000819;N-(1-hydroxy-2-methyl-propan-2-yl)-2-methoxy-benzamide;N-(1-hydroxy-2-methylpropan-2-yl)-2-methoxybenzamide;N-(2-hydroxy-1,1-dimethyl-ethyl)-2-methoxy-benzamide;N-(2-hydroxy-1,1-dimethylethyl)-2-methoxybenzamide;Oprea1_589974
• CAS NO: 74201-13-1
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.27
• Mol File: 74201-13-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 129-131°C
• Boiling Point: 400.5°C at 760 mmHg
• Flash Point: 196°C
• Appearance: /
• Density: 1.111g/cm³
• Vapor Pressure: 3.91E-07mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE(74201-13-1)
• EPA Substance Registry System: N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE(74201-13-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 74201-13-1(Hazardous Substances Data)

Usage

General Description

N-(2-Hydroxy-1,1-dimethylethyl)-2-methoxybenzenecarboxamide is a chemical compound that belongs to the class of organic compounds known as salicylamides. It is also known by its chemical formula C15H21NO3 and has a molecular weight of 263.33 g/mol. This chemical is commonly used in the pharmaceutical and medical industry. It is used as an active ingredient in various medications and topical creams due to its anti-inflammatory and analgesic properties. Additionally, it has been found to have potential applications in the treatment of conditions such as arthritis, muscle pain, and other inflammatory disorders.

InChI:InChI=1/C12H17NO3/c1-12(2,8-14)13-11(15)9-6-4-5-7-10(9)16-3/h4-7,14H,8H2,1-3H3,(H,13,15)

Upstream product

• 579-75-9 2-Methoxybenzoic acid 

Downstream Products

• 114799-75-6 EXP 8623 
• 114799-17-6 2-butyl-1-<(2'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole-5-carboxamide 
• 114798-27-5 2-butyl-4-chloro-5-hydroxymethyl-1-[(2'carboxybiphenyl-4-yl)methyl]imidazole 
• 128764-54-5 5-<<4-<<3-(N-isopropylamino)-2-hydroxypropyl>oxy>indole-2-carboxamido>methyl>-2-butyl-1-<(2'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole 
• 128764-55-6 5-<<4-<<3--2-hydroxypropyl>oxy>indole-2-carboxamido>methyl>-2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloroimidazole 
• 128764-56-7 5-<<4-<<3-(N-isopropylamino)-2-hydroxypropyl>oxy>indole-2-carboxamido>methyl>-2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloroimidazole 
• 114772-71-3 2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloro-5-(chloromethyl)imidazole hydrochloride 
• 133910-00-6 2-n-Butyl-4-chloro-1-[(2'-(2-triphenylmethyl-2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-imidazole-5-carboxaldehyde 
• 124750-09-0 1-<(2'-carboxylbiphenyl-4-yl)methyl>-5-(hydroxymethyl)-4-methyl-2-propylimidazole hydrochloride 
• 124750-13-6 2-butyl-4-chloro-1-<<2'-(1H-tetrazol-5-yl)biphenyl-4-yl>methyl>imidazole-5-carboxaldehyde benzenesulfonylhydrazone 
• 114772-63-3 1-<<2'-(tert-butoxycarbonyl)biphenyl-4-yl>methyl>-2-butyl-5-<<(2-methoxyethoxy)methoxy>methyl>-4-(trifluoromethyl)imidazole 
• 133909-99-6 2-n-butyl-4-chloro-1-[(2'-(2-triphenylmethyl-2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-imidazole-5-methanol 
• 124750-41-0 2-butyl-1-<(2'-carbomethoxybiphenyl-4-yl)methyl>-4-chloro-5-<<<(1-naphthylamino)carbonyl>amino>methyl>imidazole 
• 114799-31-4 2-butyl-1-<(2'-carboxybiphenyl-4-yl)methyl>-4-chloro-5-<<<(1-naphthylamino)carbonyl>amino>methyl>imidazole 

Relevant articles and documents

Palladium-catalyzed electrophilic C–H fluorination of arenes using oxazoline as a removable directing group

Dimethyloxazoline was rationally designed to act as a removable ortho-directing group (DG) for the palladium-catalyzed C–H electrophilic fluorination of arenes. Using NFSI as the fluorinating agent, and Pd(II), Ag(I) catalytic system, electrophilic C(sp2–H) ortho-fluorination took place on a variety of aryl substrates to afford the corresponding mono- and di-fluorinated products.

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