74205-29-1

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(3-Methoxy-phenyl)-cyclopropanecarboxylic acid is used as a starting material for the synthesis of various pharmaceuticals and organic compounds. Its unique structural features make it a valuable component in the development of new drugs and chemical products.
Used in Organic Chemistry Research:
In the field of organic chemistry, 1-(3-Methoxy-phenyl)-cyclopropanecarboxylic acid serves as a key intermediate in the synthesis of complex organic molecules. Its cyclopropane ring and methoxy-substituted phenyl group provide opportunities for further functionalization and exploration of novel chemical reactions.
Used in Drug Discovery:
Due to its potential biological activities and therapeutic properties, 1-(3-Methoxy-phenyl)-cyclopropanecarboxylic acid may be employed in drug discovery efforts. Its structural features could be leveraged to design and develop new pharmaceutical agents with specific therapeutic targets and applications.
Used in Laboratory Education:
1-(3-Methoxy-phenyl)-cyclopropanecarboxylic acid can be utilized as a teaching tool in laboratory courses and educational settings. Its synthesis and manipulation can help students understand the principles of organic chemistry and the importance of safety in laboratory practices.

Upstream product

• 74205-01-9 1-(3-methoxyphenyl)cyclopropanecarbonitrile 
• 19924-43-7 3-methoxyphenylacetonitrile 

Downstream Products

• 1083168-98-2 N-(6'-methoxy-3,5'-dimethyl-2,3'-bipyridin-6-yl)-1-(3-methoxyphenyl)cyclopropanecarboxamide 
• 1083168-58-4 1-(3-methoxyphenyl)-N-(5-methyl-6-(5-methyl-6-oxo-1,6-dihydropyridin-3-yl)pyridin-2-yl)cyclopropanecarboxamide 
• 1624333-37-4 (1-(3-methoxyphenyl)cyclopropyl)(trifluoromethyl)sulfane 
• 1268444-73-0 (4R)-4-[(2-chlorophenyl)sulfonyl]-N-(1-cyanocyclopropyl)-1-{[1-(3-methoxyphenyl)cyclopropyl]carbonyl}-L-prolinamide 
• 61492-22-6 (2S,5R,6R)-6-{[1-(3-Methoxy-phenyl)-cyclopropanecarbonyl]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 108098-17-5 (6R,7R)-7-{[1-(3-Methoxy-phenyl)-cyclopropanecarbonyl]-amino}-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 63201-08-1 C₁₁H₁₁ClO₂ 

Relevant academic research and scientific papers

Chiral Bidentate Boryl Ligand Enabled Iridium-Catalyzed Enantioselective C(sp3)-H Borylation of Cyclopropanes

We herein report an Ir-catalyzed enantioselective C(sp3)-H borylation of cyclopropanecarboxamides using a chiral bidentate boryl ligand for the first time. A variety of substrates with α-quaternary carbon centers could be compatible in this reaction to provide β-borylated products with good to excellent enantioselectivities. We have also demonstrated that the borylated products can be used as versatile precursors engaging in stereospecific transformations of C-B bonds, including the synthesis of a bioactive compound Levomilnacipran.

Electrophilic Bromolactonization of Cyclopropyl Diesters Using Lewis Basic Chalcogenide Catalysts

An efficient and regioselective electrophilic bromolactonization of cyclopropylmethyl diesters using triphenylphosphine sulfide (Ph3PS) or diphenyl selenide (Ph2Se) as the Lewis basic chalcogenide catalyst has been developed. It was observed that Ph3PS favored the formation of anti-diastereomer and yielded the multi-functional γ-lactones. Interestingly, the diastereoselectivity was reversed when using Ph2Se as a catalyst where the syn-product instead of the anti-product was favored. (Figure presented.).

Rhodium-Catalyzed Enantioselective Silylation of Cyclopropyl C?H Bonds

Hydrosilyl ethers, generated in situ by the dehydrogenative silylation of cyclopropylmethanols with diethylsilane, undergo asymmetric, intramolecular silylation of cyclopropyl C?H bonds in high yields and with high enantiomeric excesses in the presence of

FUSED HETEROCYCLIC COMPOUND

The present invention provides a compound represented by the formula: wherein R1ais a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by-NR6a-CO-(CH2) n-SO2

SUBSTITUTED ARYLPYRAZOLOPYRIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME

The invention relates to substituted arylpyrazolopyridines according to the general formula (I) : in which A, B, D, E, Ra, R1, R2, R3, R4, R5 and q are as defined in the claims, and salts t