742062-06-2

Upstream product

• 742062-04-0 (+)-(4R)-1-acetyloxy-5-benzyloxy-4-(tert-butyldimethylsilyloxy)-pentan-2-one 
• 742062-03-9 (+)-(4R)-5-benzyloxy-4-(tert-butyldimethylsilyloxy)-1-hydroxy-pentan-2-one 
• 253184-93-9 (-)-(2R)-1-benzyloxy-2-(tert-butyldimethylsilyloxy)pent-4-ene 
• 742062-05-1 (+)-(4R)-1-acetyloxy-5-benzyloxy-4-hydroxy-pentan-2-one 
• 14618-80-5 (R)-benzyl glycidol 
• 58931-16-1 (R)-1-benzyloxypent-4-en-2-ol 

Downstream Products

• 742062-07-3 (+)-acetic acid [(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]methyl ester 
• 742062-13-1 (8R)-1-[(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]-8-(tert-butyldimethylsilyloxy)-non-2-yne-1,4-diol 
• 742062-12-0 1-[(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]-prop-2-yn-1-ol 
• 742062-02-8 (+)-(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde 
• 188048-36-4 (+)-[(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]methanol 

Relevant academic research and scientific papers

Convergent highly stereoselective preparation of the C12-C24 fragment of macrolactin A

The convergent synthesis of the C12-C24 fragment (lower part) of macrolactin A is described. The adapted strategy allowed building up the lower moiety by the assembly of three key intermediates via organometallic addition. One hydroxylic stereogenic cente