253184-93-9

Basic information

• Product Name: (-)-(2R)-1-benzyloxy-2-(tert-butyldimethylsilyloxy)pent-4-ene
• Synonyms: (-)-(2R)-1-benzyloxy-2-(tert-butyldimethylsilyloxy)pent-4-ene
• CAS NO: 253184-93-9
• Molecular Weight: 306.521
• Mol File: 253184-93-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (-)-(2R)-1-benzyloxy-2-(tert-butyldimethylsilyloxy)pent-4-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(2R)-1-benzyloxy-2-(tert-butyldimethylsilyloxy)pent-4-ene(253184-93-9)
• EPA Substance Registry System: (-)-(2R)-1-benzyloxy-2-(tert-butyldimethylsilyloxy)pent-4-ene(253184-93-9)

Safety Data

• Hazardous Substances Data: 253184-93-9(Hazardous Substances Data)

Upstream product

• 58931-16-1 (R)-1-benzyloxypent-4-en-2-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 14618-80-5 (R)-benzyl glycidol 

Downstream Products

• 98892-19-4 5-benzyloxy 4R-t-butyldimethylsiloxy 1-pentanol 
• 742062-03-9 (+)-(4R)-5-benzyloxy-4-(tert-butyldimethylsilyloxy)-1-hydroxy-pentan-2-one 
• 253184-98-4 1,11-dibenzyloxy 2R,10S-di-(t-butyldimethylsiloxy)-6-undecanol 
• 253184-99-5 1,11-dibenzyloxy 2R,10S-di-(t-butyldimethysiloxy)-6-undecanone 
• 253184-96-2 5-benzyloxy 4R-t-butyldimethylsiloxy 1-pentyl cyanide 
• 253184-95-1 5-benzyloxy 4R-t-butyldimethylsiloxy 1-pentyl bromide 
• 253184-97-3 5-benzyloxy 4R-t-butyldimethylsiloxy 1-hexanal 
• 742062-13-1 (8R)-1-[(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]-8-(tert-butyldimethylsilyloxy)-non-2-yne-1,4-diol 
• 742062-04-0 (+)-(4R)-1-acetyloxy-5-benzyloxy-4-(tert-butyldimethylsilyloxy)-pentan-2-one 
• 742062-07-3 (+)-acetic acid [(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]methyl ester 
• 742062-12-0 1-[(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]-prop-2-yn-1-ol 
• 742062-06-2 (+)-(2R,4R)-5-acetyloxy-1-benzyloxy-2,4-pentanediol 
• 742062-05-1 (+)-(4R)-1-acetyloxy-5-benzyloxy-4-hydroxy-pentan-2-one 
• 742062-02-8 (+)-(4R,6R)-6-benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde 

Relevant articles and documents

Convergent highly stereoselective preparation of the C12-C24 fragment of macrolactin A

The convergent synthesis of the C12-C24 fragment (lower part) of macrolactin A is described. The adapted strategy allowed building up the lower moiety by the assembly of three key intermediates via organometallic addition. One hydroxylic stereogenic cente

Stereocontrolled synthesis of a novel pharmacophore of the tubulin- depolymerizing marine natural product spongistatin

We report here the synthesis and X-ray structure of a novel spiroketal pyran, SPIKET-P1, as a pharmocophore for the tubulin-depolymerizing marine natural product spongistatin 1. Following its retro-synthetic analysis, SPIKET-P1 was prepared using a versatile 11-step synthetic scheme in a stereocontrolled fashion. (C) 2000 Elsevier Science Ltd.