74212-25-2

Upstream product

• 74212-24-1 (3aR,4S,6R,6aS)-2,2-Dimethyl-6-(toluene-4-sulfonylamino)-tetrahydro-cyclopenta[1,3]dioxole-4-carboxylic acid methyl ester 
• 4083-64-1 Tosyl isocyanate 
• 89366-20-1 Methyl N-(p-tolylsulfonyl)iminoacetate 
• 133344-23-7 [(1R,2R,6S,7R,9R)-4,4-Dimethyl-8-(toluene-4-sulfonyl)-3,5-dioxa-8-aza-tricyclo[5.2.1.0^2,6]dec-9-yl]-carbamic acid benzyl ester 
• 133344-18-0 (1R,2R,6S,7R,9R)-4,4-Dimethyl-8-(toluene-4-sulfonyl)-3,5-dioxa-8-aza-tricyclo[5.2.1.0^2,6]decane-9-carboxylic acid ethyl ester 
• 133344-20-4 (1R,2R,6S,7R,9R)-4,4-Dimethyl-8-(toluene-4-sulfonyl)-3,5-dioxa-8-aza-tricyclo[5.2.1.0^2,6]decane-9-carbonyl chloride 
• 133344-19-1 (1R,2R,6S,7R,9R)-4,4-Dimethyl-8-(toluene-4-sulfonyl)-3,5-dioxa-8-aza-tricyclo[5.2.1.0^2,6]decane-9-carboxylic acid 
• 133344-22-6 (1R,2R,6S,7R,9R)-9-Isocyanato-4,4-dimethyl-8-(toluene-4-sulfonyl)-3,5-dioxa-8-aza-tricyclo[5.2.1.0^2,6]decane 
• 133344-08-8 (1S,3S,4R)-2-(Toluene-4-sulfonyl)-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

IMINO DIELS-ALDER CYCLOADDITIONS: AN APPLICATION TO THE SYNTHESIS OF (+/-)-ARISTEROMYCIN

A formal synthesis of (+/-)-aristeromycin starting from the imino Diels-Alder cycloadduct 3a has been achieved with high overall yield.A novel method for the in situ preparation of N-sulfonylimines is reported.

A CONVENIENT ROUTE TO CARBOCYCLIC ANALOGS OF NUCLEOSIDES: (+/-) ARISTEROMYCIN

Stereocontrolled elaboration of cyclopentadien-azomethine adducts 1 and 2 led to a short total synthesis of (+/-) aristeromycin.In the course of this work a novel zinc reduction was observed.Also, ozonolysis of the gem-dihalo olefin 10 in metha