74219-28-6

Basic information

• Product Name: Cyclohexanone, 2-hydroxy-5-methyl-2-(1-methylethyl)-
• CAS NO: 74219-28-6
• Molecular Formula: C10H18O2
• Molecular Weight: 170.252
• Mol File: 74219-28-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-hydroxy-5-methyl-2-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-hydroxy-5-methyl-2-(1-methylethyl)-(74219-28-6)
• EPA Substance Registry System: Cyclohexanone, 2-hydroxy-5-methyl-2-(1-methylethyl)-(74219-28-6)

Safety Data

• Hazardous Substances Data: 74219-28-6(Hazardous Substances Data)

Upstream product

• 1196-31-2 (1R,4R)-(+)-isomenthone 
• 10458-14-7 (2R,5S)-menthone 
• 619-52-3 (1R)-menth-3-ene 
• 20144-45-0 menthone enol acetate 
• 491-07-6 (+/-)-menthone 
• 3391-87-5 l-menthone 
• 1403609-38-0 (2S,5S)-5-methyl-1-oxo-2-(propan-2-yl)cyclohex-2-yl acetate 
• 1403461-38-0 (1S,2R,5S)-1,2-epoxy-5-methyl-2-(propan-2-yl)cyclohex-1-yl acetate 
• 213550-05-1 (5S)-5-methyl-2-(propan-2-yl)cyclohex-1-en-1-yl acetate 
• 1403609-39-1 (2R,5S)-5-methyl-1-oxo-2-(propan-2-yl)cyclohex-2-yl acetate 
• 53771-94-1 (5R)-5-methyl-2-(propan-2-yl)cyclohex-1-en-1-yl acetate 
• 1403461-36-8 (1R,2S,5R)-1,2-epoxy-5-methyl-2-(propan-2-yl)cyclohex-1-yl acetate 
• 57426-90-1 Acetic acid (R)-1-isopropyl-4-methyl-2-oxo-cyclohexyl ester 
• 79665-03-5 3,4-epoxy-p-menth-3-yl acetate 

Downstream Products

• 5113-68-8 (+/-)-p-menth-4-en-3-one-(2,4-dinitro-phenylhydrazone) 
• 7647-94-1 (1R,3R,4S)-p-menthane-3,4-diol 
• 6070-07-1 (1R,3S,4R)-p-menthane-3,4-diol 
• 7599-95-3 4β-hydroxy-l-menthol 
• 5113-68-8 (R)-p-menth-4-en-3-one-(2,4-dinitro-phenylhydrazone) 

Relevant articles and documents

One-pot anodic lactonization of Fenchone and Menthone and electrosynthesis of a new magnolione analogue

The terpenoid cycloalkanones Fenchone and Menthone have been oxidized at a platinum anode under neutral and alkaline electrolyte conditions. When NaClO4 was used as electrolyte, Fenchone (1a) afforded 1-isopropyl-4-methyl-2-oxa-bicyclo[2.2.1]he

Enantioselectivity in the Biotransformation of Mono- and Bicyclic Monoterpenoids with the Cultured Cells of Nicotiana tabacum

The biotransformation of the enantiomeric pairs of p-menthane and bicyclo and heptane derivatives with the cultured cells of Nicotiana tabacum was investigated.It was found that (i) the cultured cells discriminate the enantiomers of p-menthan-2-ol and bicycloheptan-2-ol and bicycloheptan-3-ol derivatives, and enantioselectively convert these alcohols to the corresponding ketones, (ii) the cells reduce the carbonyl group of p-methan-2-one derivatives to a high extent, but not that of p-menthan-3-ones, and (iii) the cells discriminate the enantiomers of bicyclohept-2-en-4-one (verbenone) and enantioselectively reduce the C-C double bond of the (1S,5S)-enantiomer.

Stereoselectivity in Oxidative and Reductive Transformations of p-Menthane Derivatives with the Cultured Cells of Nicotiana tabacum

The biotransformation of the enantiomeric pairs of 2- and 3-oxygenated p-methane derivatives with the cultured cells of Nicotiana tabacum was investigated.It was found that (I) the cultured cells transform only 2-oxygenated p-menthane derivatives to a great extent, (ii) the cultured cells cause the highly stereospecific reduction for (1R,4R)-2-oxo-p-menthane, whereas this is not the case for its enantiomer, and (iii) the cultured cells enantioselectively oxidize the hydroxyl group of 2-hydroxyl-p-methanes.