74231-65-5 Usage
General Description
4-(Dichloromethyl)benzonitrile is a chemical compound with the molecular formula C8H5Cl2N. It is a colorless to pale yellow liquid with a faint odor, and it is commonly used as an intermediate in the production of various pharmaceuticals, agrochemicals, and dyes. The compound is known for its strong reactivity and is considered hazardous to human health and the environment. It is classified as a potential carcinogen and may cause irritation to the skin, eyes, and respiratory system upon exposure. Additionally, 4-(dichloromethyl)benzonitrile is harmful if ingested, and proper safety precautions should be taken when handling and storing this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 74231-65-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,2,3 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 74231-65:
(7*7)+(6*4)+(5*2)+(4*3)+(3*1)+(2*6)+(1*5)=115
115 % 10 = 5
So 74231-65-5 is a valid CAS Registry Number.
74231-65-5Relevant articles and documents
Formamide Catalysis Facilitates the Transformation of Aldehydes into Geminal Dichlorides
Huy, Peter Helmut
supporting information, p. 2474 - 2483 (2019/06/08)
Herein, a novel method for the transformation of aldehydes into geminal dichlorides based on phthaloyl chloride as reagent and N -formylpyrrolidine as Lewis base catalyst is disclosed. Given the mild reaction conditions, the current protocol is distinguished by high levels of functional group compatibility and scalability and is operationally simple. The in situ formation of a Vilsmeier Haack reagent type intermediate is likely to be essential for this organocatalytic nucleophilic substitution reaction.
A simple and efficient procedure for the preparation of benzal chlorides and benzal bromides
Léonel, Eric,Paugam, Jean-Paul,Heintz, Monique,Nédélec, Jean-Yves
, p. 4015 - 4024 (2007/10/03)
Benzal chlorides and benzal bromides were conveniently synthesized by reaction of aryl aldehydes with a Vilsmeier type reagent formed in situ by reduction of CCl4 or CBr4 in dimethylformamide (DMF) as solvent.
