74254-66-3Relevant academic research and scientific papers
A structure-taste study of arylsulfonyl(cyclo)alkanecarboxylic acids
Lysiak, Violetta,Ratajczak, Aleksander,Mencel, Agnieszka,Jarzembek, Krystyna,Polanski, Jaroslaw
, p. 671 - 675 (2007/10/03)
A number of sweeteners contain a sulfonyl group. In our current search for new glucophores several new compounds containing such group were obtained. A series of novel 1-phenylsulfonylcyklohexanecarboxylic acids and 2-arylsulfonylalkanecarboxylic acids was obtained and evaluated for their sweet taste quality. It has been found that methyl substituents are of the key importance for the activity of these compounds.
SYNTHESIS OF THE NITRILES AND AMIDES OF 1-(ARYLSULFONYL)CYCLOALKANESCARBOXYLIC ACIDS
Neplyuev, V. M.,Bazavova, I. M.,Esipenko, A. N.,Lozinskii, M. O.
, p. 1712 - 1716 (2007/10/02)
1-Arylsulfonylcycloalkanecarbonitriles were synthesized by the cycloalkylation of arylsulfonylacetonitriles by terminal dihalogenoalkanes under the conditions of phase-transfeer catalysis.Hydrolysis of the products gave 11-arylsulfonylcycloalkanecarboxyli
ALKYLATION OF ETHYL ARYLSULFONYLACETATES IN CATALYTIC TWO-PHASE SYSTEM
Ratajczak, Aleksander,Polanski, Jaroslaw
, p. 1963 - 1971 (2007/10/02)
It was found that ethyl arylsulfonylacetates could be easily dialkylated or cyclodialkylated in catalytic two-phase systems with concentrated aqueous sodium hydroxide, undergoing no hydrolysis under the reaction conditions.
