74254-66-3

Basic information

• Product Name: Cyclohexanecarboxylic acid, 1-(phenylsulfonyl)-
• CAS NO: 74254-66-3
• Molecular Formula: C13H16O4S
• Molecular Weight: 268.334
• Mol File: 74254-66-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 1-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 1-(phenylsulfonyl)-(74254-66-3)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 1-(phenylsulfonyl)-(74254-66-3)

Safety Data

• Hazardous Substances Data: 74254-66-3(Hazardous Substances Data)

Upstream product

• 111-24-0 1,5-dibromo-pentane 
• 7605-30-3 ethyl 2-phenylsulfonylacetate 
• 140458-97-5 1-phenylsulfonylcyclohexanecarboxylic acid ethyl ester 
• 141642-46-8 1-phenylsulfonylcyclohex-3-ene 
• 5535-48-8 PVS 
• 124-38-9 carbon dioxide 
• 6947-57-5 cyclohexyl phenyl sulfone 

Relevant articles and documents

A structure-taste study of arylsulfonyl(cyclo)alkanecarboxylic acids

A number of sweeteners contain a sulfonyl group. In our current search for new glucophores several new compounds containing such group were obtained. A series of novel 1-phenylsulfonylcyklohexanecarboxylic acids and 2-arylsulfonylalkanecarboxylic acids was obtained and evaluated for their sweet taste quality. It has been found that methyl substituents are of the key importance for the activity of these compounds.

ALKYLATION OF ETHYL ARYLSULFONYLACETATES IN CATALYTIC TWO-PHASE SYSTEM

It was found that ethyl arylsulfonylacetates could be easily dialkylated or cyclodialkylated in catalytic two-phase systems with concentrated aqueous sodium hydroxide, undergoing no hydrolysis under the reaction conditions.