74264-88-3

Basic information

• Product Name: 6-O-tert-butyldimethylsilanyl-1-O-methyl-β-D-glucopyranoside
• Synonyms: 6-O-tert-butyldimethylsilanyl-1-O-methyl-β-D-glucopyranoside
• CAS NO: 74264-88-3
• Molecular Weight: 308.447
• Mol File: 74264-88-3.mol
• Article Data: 39

Chemical Properties

• CAS DataBase Reference: 6-O-tert-butyldimethylsilanyl-1-O-methyl-β-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 6-O-tert-butyldimethylsilanyl-1-O-methyl-β-D-glucopyranoside(74264-88-3)
• EPA Substance Registry System: 6-O-tert-butyldimethylsilanyl-1-O-methyl-β-D-glucopyranoside(74264-88-3)

Safety Data

• Hazardous Substances Data: 74264-88-3(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 82112-21-8 N,O-bis(tertbutyldimethylsilyl)acetamide 
• 143422-89-3 (2-methylallyl)tertiobutyl-dimethylsilane 
• 1824-94-8 methyl beta-D-galactopyranoside 
• 29681-57-0 tert-butyldimethylsilane 

Downstream Products

• 97-30-3 methyl-alpha-D-glucopyranoside 
• 63734-11-2 acetic acid 3,5-diacetoxy-2-(tert-butyldimethylsilanyloxymethyl)-6-methoxytetrahydropyran-4-yl ester 
• 1340482-37-2 methyl 2-O-(2',3',4',6'-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranoside 
• 1340482-38-3 methyl 2-O-(2',3',4',6'-tetra-O-benzyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 1340482-39-4 methyl 3-O-(2',3',4',6'-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranoside 
• 1340482-40-7 methyl 3-O-(2',3',4',6'-tetra-O-benzyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 1372890-62-4 methyl 6-(tert-butyldimethylsilyloxy)-3-O-(4-toluenesulfonyl)-β-D-galactopyranoside 
• 1610558-83-2 methyl 6-(tert-butyldimethylsilyloxy)-3-O-(benzoyl)-β-D-galactopyranoside 
• 521294-03-1 hexane-1,6-diyl bis(phenylacetate) 
• 71512-68-0 methyl 1,2,4-tri-O-acetyl-6-O-benzyl-α-D-glucopyranoside 

Relevant articles and documents

Discriminating non-ylidic carbon-sulfur bond cleavages of sulfonium ylides for alkylation and arylation reactions

A sulfonium ylide participated alkylation and arylation under transition-metal free conditions is described. The disparate reaction pattern allowed the separate activation of non-ylidic S-alkyl and S-aryl bond. Under acidic conditions, sulfonium ylides serve as alkyl cation precursors which facilitate the alkylations. While under alkaline conditions, cleavage of non-ylidic S-aryl bond produces O-arylated compounds efficiently. The robustness of the protocols were established by the excellent compatibility of wide variety of substrates including carbohydrates.

Synthesis and biological evaluation of 1,6-bis-triazole-2,3,4-tri-O-benzyl-α-D-glucopyranosides as a novel α-glucosidase inhibitor in the treatment of Type 2 diabetes

A novel series of 1,6-bis-triazole-benzyl-α-glucoside derivatives (7a-7ee) were designed, synthesized and evaluated for inhibitory activity against α-glucosidase. Most of the synthesized compounds exhibited good activity with IC50 ranging from

Using DMF as Both a Catalyst and Cosolvent for the Regioselective Silylation of Polyols and Diols

Highly regioselective silylation of primary hydroxyl groups of unprotected polyols and diols was obtained by the use of a mixed solvent of MeCN/DMF (10:1) in this study. DMF was discovered to be a good catalyst in this reaction, although the silylation us