74268-53-4

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 33992-53-9 (1-chloroprop-2-yn-1-yl)benzene 
• 104846-76-6 (±)-methyl (1-phenylprop-2-yn-1-yl) carbonate 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 103-80-0 phenylacetyl chloride 
• 623-73-4 diazoacetic acid ethyl ester 
• 536-74-3 phenylacetylene 
• 186581-53-3 diazomethane 
• 57585-08-7 4-phenyl-2,3-allenoic acid 
• 18942-24-0 4-Phenyl-2,3-butadienenitrile 
• 57585-08-7 (aS)-4-phenyl-2,3-allenoic acid 
• 1360733-32-9 methyl 4-oxo-1-phenylbut-2-yn-1-yl carbonate 
• 1779-58-4 (methyloxycarbonylmethyl)triphenylphosphonium bromide 

Downstream Products

• 13901-79-6 methyl 1-methyl-2,5-diphenylpyrrole-3-carboxylate 
• 1262883-80-6 (Z)-methyl 4-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-enoate 

Relevant academic research and scientific papers

A copper-catalyzed diastereoselective O-transfer reaction of: N -vinyl-α,β-unsaturated nitrones with ketenes into γ-lactones through [5 + 2] cycloaddition and N-O bond cleavage

A general protocol for the construction of novel densely functionalized γ-lactones was developed in good to excellent yields with high diastereoselectivity from easily available N-vinyl-α,β-unsaturated nitrones and ketenes. The reaction involves copper-catalyzed [5 + 2] cycloaddition, N-O bond cleavage, 6π electron cyclization, and aromatization to afford various γ-(pyridin-2-yl)lactones over four step transformations in a single flask. The present method features mild reaction conditions, high atom economy, high regio- and diastereoselectivity, diversity of γ-lactones, and a new application of the O-transfer reaction.

Biotransformations of racemic 2,3-allenenitriles in biphasic systems: Synthesis and transformations of enantioenriched axially chiral 2,3-allenoic acids and their derivatives

Catalyzed by Rhodococcus erythropolis AJ270 whole cells in an aqueous phosphate buffer-n-hexane biphasic system, racemic axially chiral 2,3-allenenitriles underwent hydrolysis to afford enantioenriched (aR)-2,3-allenamides and (aS)-2,3-allenoic acids with

N -heterocyclic carbene-catalyzed internal redox reaction of alkynals: An efficient synthesis of allenoates

An efficient N-heterocyclic carbene (NHC)-catalyzed internal redox reaction of alkynals that bear a γ leaving group has been developed. This process provides a new access to a range of allenoates in good yields. Preliminary results demonstrate that the en

Regio- and stereoselective copper-catalyzed β-borylation of allenoates by a preactivated diboron

A mild and efficient copper-catalyzed borylation of electron deficient allenoates using an sp2-sp3 mixed hybridized diboron regioselectively installs a boron moiety on the β-position with exclusive (Z)-double bond geometry.

CONVENIENT SYNTHESIS OF ALLENYL ESTERS AND AMIDES BY PALLADIUM CATALYZED ALKOXY- AND AMIDO-CARBONYLATION OF ALLENYL AND PROPYNYL HALIDES

Allenyl esters R1R2C=C=C(H)C(O)R (R=OMe) or amides (R=NEt2) are formed with excellent selectivities and in good yields by carbonylation of propynyl and allenyl halides at 1-20 bar CO pressure in benzene, in the presence of MeOH or HNEt2 and 1percent of Pd

PALLADIUM-CATALYZED CARBONYLATION OF PROPARGYLIC CARBONATES: PREPARATION OF 2,3- AND 2,4-DIENYL CARBOXYLATES

Propargylic carbonates are converted to 2,3-dienyl carboxylates by the palladium-catalyzed decarboxylation-carbonylation in alcohol under mild conditions.In ether, 2,4-dienyl carboxylates are obtained.

Eine einfache Allencarbonsaeureester-Synthese mittels der Wittig-Reaktion

A simple one-pot synthesis of variously substituted α-allenic esters (7-23, cf.Scheme 4) is described.Either of the phosphonium salts 1 and 2 or the phosphoranes 3-6 in methylene chloride (or acetonitrile) when treated with acid chlorides at room temperat