74270-78-3

Usage

Uses

Used in Pharmaceutical Industry:
4-Benzyl-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol is used as a pharmaceutical agent for its antiviral, antifungal, antimicrobial, and anti-inflammatory properties. Its diverse biological activities make it a promising candidate for the development of new drugs to treat various diseases and infections.
Used in Agrochemical Industry:
4-Benzyl-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol is used as an agrochemical agent for its potential applications in agriculture, such as fungicides, pesticides, and antimicrobial agents. Its biological activities can help protect crops from various pathogens and pests, contributing to increased crop yields and food security.
Used in Organic Chemistry Research:
4-Benzyl-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol is used as a building block in the synthesis of complex organic molecules. Its unique structure and functional groups make it a valuable tool for researchers in the field of organic chemistry, enabling the development of new compounds and materials with potential applications in various industries.

InChI:InChI=1/C14H12N4S/c19-14-17-16-13(12-6-8-15-9-7-12)18(14)10-11-4-2-1-3-5-11/h1-9H,10H2,(H,17,19)

Upstream product

• 100-46-9 benzylamine 
• 15264-63-8 5-(4-pyridinyl)-1,3,4-oxadiazole-2-thiol 
• 63932-07-0 N⁴-benzyl-iso-nicotinic acid thio-semicarbazide 
• 54-85-3 isoniazid 
• 622-78-6 Benzyl isothiocyanate 
• 211572-59-7 N-benzyl-2-(pyridin-3-ylcarbonyl)hydrazinecarbothioamide 

Downstream Products

• 129579-69-7 C₄₇H₆₄N₄O₃S 
• 386746-92-5 N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-5-(4-pyridyl)-4-benzyl-1,2,4-triazole-2-thione 
• 1352049-54-7 2-[-4-benzyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-ylthio]-N⁽²⁾-[1-methyl-3-oxobutilidin]acetohydrazine 
• 431884-59-2 1-[(4-benzyl)-5-(4-pyridyl)-4H-1,2,4-triazol-3-ylthiomethylcarboxyl]-3,5-dimethyl-1H-pyrazole 
• 1352049-65-0 5-[4-benzyl-5-(4-pyridyl)-1,2,4-triazole-3-ylthiomethyl]-1,3,4-oxadiazole-2-thiol 
• 359010-77-8 C₁₆H₁₆N₆OS 
• 440637-99-0 (4-benzyl-5-(4-pyridyl)-4H-1,2,4-triazol-3-yl) ethyl sulfide 
• 74271-12-8 (4-benzyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetic acid ethyl ester 

Relevant academic research and scientific papers

Design, Synthesis and Antibacterial Evaluation of 1-[(1R,2S)-2-Fluorocyclopropyl]ciprofloxacin-1,2,4-triazole-5(4H)-thione Hybrids

A new class of 1-[(1R,2S)-2-fluorocyclopropyl]ciprofloxacin (CPFX)-1,2,4-triazole-5(4H)-thione hybrids 6a?–?6o was designed, synthesized and evaluated for their in?vitro antibacterial activities against a panel of clinically important drug-sensitive and d

Design, synthesis, and herbicidal activities of 3-aryl-4-substituted-5-[3- (trifluoromethyl)phenoxy]-1,2,4-triazoles

In order to find novel bleaching herbicide lead compounds, a series of novel 3-aryl-4-substituted-5-[3-(trifluoromethyl)phenoxy]-1,2,4-triazoles were designed and synthesized by the multi-step reactions. N-(Arylformamido) phenylthioureas undergo ring clos

The microwave-assisted dehydrative cyclization of thiosemicarbazides forming substituted 1,2,4-triazoles

Different types of 4,5-disubstituted 1,2,4-triazole-3-thiones were prepared by microwave irradiation as well as by a classical method. The beneficial effect of microwave irradiation on the dehydrative cyclization of thiosemicarbazides in different reactio

Synthesis and structure elucidation of some new thioether derivatives of 1,2,4-triazoline-3-thiones and their antimicrobial activities.

5-(4-Pyridinyl)-4-substituted-2.4-dihydro-3H-1,2,4-triazole-3-thiones and 5-(4-pyridinyl)-4-substituted-3-(benzoylmethyl)thio-4H-1,2,4-triazoles were synthesized. The structures of original nine compounds were confirmed by IR, 'H NMR, mass spectral methods and elemental analysis. The antibacterial, antifungal and antimycobacterial activities, together with those of known intermediate 1,4-disubstituted thiosemicarbazides, were reported.

Synthesis and structure determination of some oxadiazole-2-thione and triazole-3-thione galactosides

The syntheses of 5-pyridyl-3(β-D-galactopyranosyl)-1,3,4-oxadiazole-2-thiones 3a-3c and 5-pyridyl-2(β-D-galactopyranosyl)-4-benzyl-l,2, 4-triazole-3-thiones 6a-6c are reported. The existence of N-galactosides - not S-galactosides - was proven by IR and 15N NMR spectroscopy. The structures of the final products and the intermediates were elucidated by IR, 1H, 13C and 15N NMR spectroscopy and mass spectrometry.

Synthesis and antimicrobial activity of 2,4-dihydro-4-benzyl-5-(isomeric pyridyl)-3H-1,2,4-triazole-3-thiones

intramolecular cyclization of the three isomeric 1,4-disubstituted thiosemicarbazides 3a-c in aqueous sodium hydroxide affords 2,4-dihydro-4-(benzyl)-5-(isomeric pyridyl)-3H-1,2,4-triazole-3-thiones 4a-c.The antibacterial activity of these compounds has been determined against seventeen, gram positive and gram negative microorganisms.

Dopamine-beta hydroxylase inhibitors

Dopamine-β-hydroxylase inhibitors of structure: in which R1 is pyridyl or pyridylalkyl, pharmaceutical compositions containing them and their use in therapy in lowering blood pressure.