74307-73-6

Usage

Uses

Used in Pharmaceutical Industry:
Cyclobutanecarboxylic acid, 3-amino-, ethyl ester (6CI,9CI) is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical properties and reactivity make it a valuable component in the development of new drugs and medications.
Used in Agrochemical Industry:
Cyclobutanecarboxylic acid, 3-amino-, ethyl ester (6CI,9CI) also serves as an essential building block in the production of agrochemicals. Its role in the synthesis of various agrochemicals contributes to its use in agriculture for pest control and crop protection.
Used in Organic Compound Production:
Cyclobutanecarboxylic acid, 3-amino-, ethyl ester (6CI,9CI) is employed as a versatile building block in the creation of a wide range of organic compounds. Its unique structure and reactivity allow for its use in various chemical reactions, leading to the formation of diverse organic molecules for different applications.

Upstream product

• 98431-84-6 ethyl 3-(hydroxyimino)cyclobutanecarboxylate 
• 957793-34-9 ethyl 3-(dibenzylamino)cyclobutane-1-carboxylate 
• 87121-89-9 ethyl 3-oxocyclobutanecarboxylate 
• 23761-23-1 3-oxocyclobutanecarboxylic acid 

Downstream Products

• 101090-54-4 3-phthalimido-cyclobutanecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

COMPOUND AS ACC INHIBITOR AND USE THEREOF

Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.

SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTANE AND 2-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

There is provided a compound of formula (I), wherein L1 to L3, R1 to R4, X, A and B have meanings given in the description, and pharmaceutically acceptable salts, solvates and prodrugs thereof, which compounds are useful as antagonists of the orexin-1 and orexin-2 receptors or as selective antagonists of the orexin-1 receptor, and thus, in particular, in the treatment or prevention of inter alia substance dependence, addiction, anxiety disorders, panic disorders, binge eating, compulsive disorders, impulse control disorders, cognitive impairment and Alzheimer's disease.

BICYCLIC HETEROCYCLE SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS

Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a bicyclic heterocycle, and R1, R3, R4, R5 and R6 are as defined herein, that are useful as kinase modulators, including IRAK-4 modulation.

HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS

Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.