7432-59-9

Basic information

• Product Name: TRANS-2-(DIETHYLAMINO)CYCLOPENTANOL
• Synonyms: TRANS-2-(DIETHYLAMINO)CYCLOPENTANOL
• CAS NO: 7432-59-9
• Molecular Formula: C₉H₁₉NO
• Molecular Weight: 157.25
• Mol File: 7432-59-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TRANS-2-(DIETHYLAMINO)CYCLOPENTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-2-(DIETHYLAMINO)CYCLOPENTANOL(7432-59-9)
• EPA Substance Registry System: TRANS-2-(DIETHYLAMINO)CYCLOPENTANOL(7432-59-9)

Safety Data

• Hazardous Substances Data: 7432-59-9(Hazardous Substances Data)

Upstream product

• 285-67-6 Cyclopentene oxide 
• 109-89-7 diethylamine 

Downstream Products

• 60093-70-1 (3-Pentyloxy-phenyl)-carbamic acid (1S,2S)-2-diethylamino-cyclopentyl ester; hydrochloride 
• 67450-57-1 N-(3,4-Dichloro-phenyl)-N-((1R,2R)-2-diethylamino-cyclopentyl)-propionamide 
• 67473-26-1 (1S,2S)-N-(3,4-Dichloro-phenyl)-N',N'-diethyl-cyclopentane-1,2-diamine 

Relevant articles and documents

A CONVENIENT PREPARATION OF β-AMINO ALCOHOLS FROM EPOXIDES AND HALOMAGNESIUM ALKYLAMIDES

Treatment of epoxides with halomagnesium alkylamides in THF affords the corresponding β-amino alcohols in good yields.

FACILE AMINOLYSIS OF EPOXIDES WITH DIETHYLALUMINUM AMIDES

Treatment of an epoxide with a diethylaluminum amide in dichloromethane at room temperature affords the corresponding β-amino alcohol in good yield.

N-(2-aminocyclopentyl)alkanoylanilides

N-(2-Aminocyclopentyl)N-alkanoylanilides and their 2-N-oxides of the formula STR1 e.g., trans-3,4-dichloro-N-[2-(dimethylamino)cyclopentyl]propionanilide, and their pharmacologically acceptable salts, have been found to possess potent Central Nervous System anti-depressant properties. Many of them are new. These compounds are promising anti-depressant drugs which are characterized by a better therapeutic ratio than imipramine, and long acting activity which may allow longer durations between administrations, e.g., once a day. Pharmaceutical compositions containing these compounds and a process for treating conditions of depression with these compositions are disclosed.