74362-00-8

Upstream product

• 79-46-9 2-nitropropane 
• 20890-16-8 (E)-1-phenyl-3-(pyridin-4-yl)prop-2-en-1-one 
• 872-85-5 pyridine-4-carbaldehyde 
• 98-86-2 acetophenone 

Downstream Products

• 61196-80-3 5,5-Dimethyl-2-phenyl-4-(4-pyridyl)-1-pyrrolin 
• 577032-18-9 4-(2,2-dimethyl-5-phenyl-3-pyrrolidinyl)-pyridine 
• 74361-85-6 4-(5',5'-Dimethyl-2'-phenyl-1'-pyrrolin-4'-yl)pyridin-1'-oxidn 
• 61196-49-4 trans-4-(2,2-dimethyl-5-phenyl-3-pyrrolidinyl)-pyridine dihydrochloride 

Relevant academic research and scientific papers

Synthesis of 2H-pyrroles by treatment of pyrrolidines with DDQ

A mild and efficient synthesis of 2,2-dialkyl-3,5-diaryl-2H-pyrroles is described. Treatment of 2,2-dialkyl-3,5-diarylpyrrolidines with DDQ in dioxane for 12-24 h at rt afforded the corresponding 2H-pyrroles in 55-81% overall yields.

NEUE WEGE ZU 1H-UND 2H-PYRROLEN

A synthesis of 1H-pyrroles is described starting with pyridine analogues of chalcones and involving the reacxtion of acetic anhydride with 1-pyrroline-1-oxides.Another route leads from 1-pyrrolines to 2H-pyrroles via bromination with N-bromosuccinimide and subsequent dehydrobromination in dimethylformamide.