74396-74-0

Usage

Uses

Used in Pharmaceutical Industry:
(3Z)-7-Chloro-1H-indole-2,3-dione 3-oxime is used as a pharmaceutical compound for its potential biological activity. It is being studied for its applications in the development of new drugs and therapies, given its unique structure and properties.
Used as a Reagent in Chemical Reactions:
In the field of chemistry, (3Z)-7-Chloro-1H-indole-2,3-dione 3-oxime serves as a reagent in various chemical reactions. Its specific characteristics allow it to participate in a range of processes, contributing to the synthesis of other compounds.
Used in Organic Synthesis:
(3Z)-7-Chloro-1H-indole-2,3-dione 3-oxime is utilized in organic synthesis as a building block for the production of various compounds. Its presence in the synthesis process can lead to the creation of new organic molecules with diverse applications.
Used in Research and Development:
(3Z)-7-Chloro-1H-indole-2,3-dione 3-oxime is also used in research and development settings to explore its potential applications and to understand its interactions with other molecules. This can lead to the discovery of new uses and properties, expanding its utility in the scientific community.

InChI:InChI=1/C8H5ClN2O2/c9-5-3-1-2-4-6(5)10-8(12)7(4)11-13/h1-3,13H,(H,10,11,12)

Upstream product

• 7477-63-6 7-chloroisatin 
• 143884-77-9 nitro-acetic acid-(2-chloro-anilide) 
• 95-51-2 o-chloroaniline 
• 14722-82-8 N-(2-chlorophenyl)-2-isonitrosoacetanilide 
• 105442-70-4 (2-Chloro-phenyl)-((E)-1-methylsulfanyl-2-nitro-vinyl)-amine 

Downstream Products

• 62484-29-1 2,4,8-trichloroquinazoline 

Relevant academic research and scientific papers

A novel strategy to the synthesis of 4-anilinoquinazoline derivatives

A novel approach to prepare 4-anilinoquinazoline derivatives based on the transformation of indoline-2,3-dione to formamidine was developed. The processes with this approach are simple, efficient, and environmentally friendly. The efficiency of this approach was evaluated by synthesizing 17 4-anilinoquinazolines and comparing the obtained yields with those achievable through conventional synthetic methods. It was the first time that compounds 8d, 8e, 8h, and 13b-f were synthesized. The characteristics of the IR and the UV spectra of these compounds and the effects of their substituents on the spectra were observed.

Pronounced ionic liquid effect in the synthesis of biologically active isatin-3-oxime derivatives under acid catalysis

An efficient method was developed for the preparation of isatin-3-oxime derivatives with Bronsted and/or Lewis acids in imidazolium-based ionic liquids. Isatin-3-oxime bearing the electron donating methoxy group was equally obtained in good yields. The pr

Synthesis of isatin 3-oximes from 2-nitroacetanilides

2-Nitroacetanilides, prepared by alkaline hydrolysis of 1-arylamino-1-methylthio-2-nitroethenes, are converted into isatin (1H-indole-2,3-dione) 3-oximes by treatment with concentrated sulfuric acid or trifluoromethanesulfonic acid at room temperature.