74418-36-3

Upstream product

• 76231-76-0 (1S,5R)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-one 
• 471-15-8 Thujone 
• 74418-34-1 4β-(Hydroxymethyl)-thujan-3-one 

Relevant academic research and scientific papers

EPIMERISIERUNG VON (-)-THUJON ZU (+)-THUJON

(-)-Thujone is quantitatively epimerized to (+)-thujone over 4-hydroximethylthujone and thujone-4-carboxylic acid.

Reaktionen des (+)-Thujons und (-)-Isothujons mit Formaldehyd

(+)-Thujone and (-)-isothujone react with formaldehyde to give 4β-(hydroxymethyl)thujone (1) and the 2-methylene derivatives 6 and 7.Oxidation of 1 gives thujone-4β-carboxylic acid (2) which decarboxylates to (+)-thujone. 1 is reduced to the isomeric 4β-(hydroxymethyl)- (3a, 3b) and 4-methylthujanols (4a, 4b). 3-Methylthujanol is oxidized to 4-methylthujone (5).