74451-73-3Relevant academic research and scientific papers
Facile synthesis of 4H-1,2,4-benzothiadiazine-1,1-dioxides
Cherepakha, Artem,Kovtunenko, Vladimir O.,Tolmachev, Andrey,Lukin, Oleg,Nazarenko, Konstantin G.
experimental part, p. 1977 - 1989 (2011/06/23)
o-Bromoarylsulfonylated amidines prepared either by acylation of amidine with o-bromoarylsulfonyl chloride or through the reaction of o-bromoarylsulfoamide with lactime ether underwent Cu(I)-catalyzed intramolecular cyclization to give 4H-1,2,4-benzothiadiazine-1,1-dioxides in good yield. By varying substituents on arylsulfonyl moieties, amidines, and lactime ethers, a small library of structurally diverse 4H-1,2,4- benzothiadiazine-1,1-dioxide derivatives was prepared.
