74458-01-8

Upstream product

• 83348-75-8 2-Formyl-2-(2,3-O-isopropyliden-5-O-trityl-D-ribofuranosyl)acetonitril 
• 6436-90-4 ethyl 2-(benzylamino)acetate 
• 74458-03-0 Methanesulfonic acid (E)-2-cyano-2-((3aS,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-vinyl ester 

Downstream Products

• 74458-06-3 3-Amino-1-benzyl-4-((3aS,4R,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1H-pyrrole-2-carboxylic acid ethyl ester 
• 74458-04-1 3-Amino-1-benzyl-4-((3aS,4S,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1H-pyrrole-2-carboxylic acid ethyl ester 
• 74469-93-5 1-Benzyl-3-(dimethylamino-methyleneamino)-4-((3aS,4S,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1H-pyrrole-2-carboxylic acid ethyl ester 
• 74458-05-2 5-Benzyl-7-((3aS,4S,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one 
• 74469-94-6 1-Benzyl-3-(dimethylamino-methyleneamino)-4-((3aS,4R,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1H-pyrrole-2-carboxylic acid ethyl ester 
• 74458-07-4 5-Benzyl-7-((3aS,4R,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one 

Relevant academic research and scientific papers

SYNTHESIS OF THE PYRROLOPYRIMIDINE C-NUCLEOSIDE ISOSTERE OF INOSINE

The synthesis of "9-deazainosine", a new C-nucleoside analog of inosine and of formycin B is described.It involves conversion of a ribosylated 3-amino-2-carboalkoxypyrrole intermediate to the desired pyrrolopyrimidine system.