74460-84-7

Basic information

• Product Name: ethyl 2,2-diMethylbut-3-ynoate
• Synonyms: ethyl 2,2-diMethylbut-3-ynoate
• CAS NO: 74460-84-7
• Molecular Formula: C₈H₁₂O₂
• Molecular Weight: 140.17968
• Mol File: 74460-84-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 2,2-diMethylbut-3-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,2-diMethylbut-3-ynoate(74460-84-7)
• EPA Substance Registry System: ethyl 2,2-diMethylbut-3-ynoate(74460-84-7)

Safety Data

• Hazardous Substances Data: 74460-84-7(Hazardous Substances Data)

Upstream product

• 4341-76-8 Ethyl 2-butynoate 
• 74-88-4 methyl iodide 
• 623-47-2 propynoic acid ethyl ester 

Downstream Products

• 5129-40-8 ethyl 2,2-dimethylbutanoate 

Relevant articles and documents

Deconjugative Alkylation of α,β-Acetylenic Esters by Electrogenerated Base

Electrolysis of ethyl propiolate (1) and an excess of methyl iodide at a platinum cathode in hexamethylphosphoric triamide (HMPA) or N,N-dimethylformamide (DMF) solution containing tetra-n-butylammonium salt gave the acetylenic esters 2, 3, and 4.Similar electrochemical reactions of α,β-acetylenic esters 2, 5, and 9 with methyl iodide took place in good yields to give the corresponding α,α-dimethyl-β,γ-acetylenic esters 3 and 4, 4, and 10, respectively.Electrochemical reactions of 5 with ethyl, butyl, and allyl iodides also gave α,α-dialkyl β,γ-acetylenic esters 6, 7, and 8, respectively.These facile deconjugative alkylations appeared to take place by the action of the electrogenerated base (EGB) which was formed by the electrochemical reduction of alkyl iodides.Alkyl iodides worked as both a probasic compound of the EGB and as an electrophile.Reaction pathways of the present deconjugative alkylations are also discussed.