7447-59-8

Basic information

• Product Name: N-ethyl-N-hydroxyaniline
• Synonyms: N-ethyl-N-hydroxyaniline;N-Ethyl-N-hydroxybenzenamine;N-Ethyl-N-phenylhydroxylamine;Einecs 231-213-9
• CAS NO: 7447-59-8
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.17904
• EINECS: 231-213-9
• Mol File: 7447-59-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 219.3°C at 760 mmHg
• Flash Point: 98.9°C
• Appearance: /
• Density: 1.098g/cm³
• Vapor Pressure: 0.0698mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: N-ethyl-N-hydroxyaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-ethyl-N-hydroxyaniline(7447-59-8)
• EPA Substance Registry System: N-ethyl-N-hydroxyaniline(7447-59-8)

Safety Data

• Hazardous Substances Data: 7447-59-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H11NO/c1-2-9(10)8-6-4-3-5-7-8/h3-7,10H,2H2,1H3

Upstream product

• 75-07-0 acetaldehyde 
• 100-65-2 N-Phenylhydroxylamine 
• 74-96-4 ethyl bromide 

Downstream Products

• 108047-26-3 5-<(Hydroxy)(phenyl)amino>-3-methyl-2-phenylisoxazolidin 
• 92115-23-6 N-ethyl-4-methoxy-N-phenylaniline 
• 91075-21-7 1-Ethyl-2-(phenylsulfonyl)methylindol 
• 104-48-3 4-methoxy-N-ethylaniline 
• 15258-43-2 N-ethyl-2-methoxyaniline 
• 101089-92-3 O-benzoyl-N-ethyl-N-phenylhydroxylamine 
• 659-34-7 (4-hydroxyphenyl)ethylamine 
• 99075-50-0 O-acetyl-N-ethyl-N-phenyl-hydroxylamine 

Relevant articles and documents

Cobalt-Catalyzed Electrophilic Amination of Aryl- and Heteroarylzinc Pivalates with N-Hydroxylamine Benzoates

Aryl- and heteroarylzinc pivalates can be aminated with O-benzoylhydroxylamines at 25 °C within 2–4 h in the presence of 2.5–5.0 % CoCl2?2 LiCl to furnish the corresponding tertiary arylated or heteroarylated amines in good yields. This electrophilic amination also provides access to diarylamines and aryl(heteroaryl)amines. A new tuberculosis drug candidate (Q203) was prepared in six steps and 56 % overall yield by using this cobalt-catalyzed amination as the key step.