74470-43-2 Usage
Uses
Used in Pharmaceutical Industry:
Methyl 5-(Methylthio)nicotinate is used as an active pharmaceutical ingredient for its antioxidant and anti-inflammatory properties. It is incorporated into medications to help treat various health conditions, such as inflammation and oxidative stress-related disorders.
Used in Skincare Industry:
Methyl 5-(Methylthio)nicotinate is used as an active ingredient in skincare products for its ability to treat skin conditions such as acne and eczema. Its antioxidant and anti-inflammatory properties help soothe and protect the skin, promoting a healthier complexion.
Used in Topical Treatments:
Methyl 5-(Methylthio)nicotinate is used as a key component in topical treatments to improve blood flow and circulation when applied to the skin. Its vasodilatory effects can help alleviate symptoms of poor circulation and promote overall skin health.
Used in Antioxidant Formulations:
Methyl 5-(Methylthio)nicotinate is used as an antioxidant in various formulations to protect the skin from free radical damage and environmental stressors. Its ability to neutralize harmful molecules helps maintain skin integrity and prevent premature aging.
Used in Anti-Inflammatory Formulations:
Methyl 5-(Methylthio)nicotinate is used as an anti-inflammatory agent in formulations designed to reduce inflammation and soothe irritated skin. Its calming effects make it an ideal ingredient for sensitive skin types and those prone to inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 74470-43-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,7 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74470-43:
(7*7)+(6*4)+(5*4)+(4*7)+(3*0)+(2*4)+(1*3)=132
132 % 10 = 2
So 74470-43-2 is a valid CAS Registry Number.
74470-43-2Relevant academic research and scientific papers
SUBSTITUTED PYRIDAZINONE FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES
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Paragraph 0251, (2021/11/20)
Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.
PYRIDAZINONE COMPOUNDS AND USES THEREOF
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Paragraph 0247, (2020/06/01)
Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.
Nicotinyl aspartyl ketones as inhibitors of caspase-3
Isabel, Elise,Black, W. Cameron,Bayly, Christopher I.,Grimm, Erich L.,Janes, Marc K.,McKay, Daniel J.,Nicholson, Donald W.,Rasper, Dita M.,Renaud, Johanne,Roy, Sophie,Tam, John,Thornberry, Nancy A.,Vaillancourt, John P.,Xanthoudakis, Steven,Zamboni, Robert
, p. 2137 - 2140 (2007/10/03)
Caspase-3 is a cysteinyl protease that mediates apoptotic cell death. Its inhibition may have an important impact in the treatment of several degenerative diseases. Since P1 aspartic acid is a required element of recognition for this enzyme, a