74476-27-0

Upstream product

• 140-11-4 Benzyl acetate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 81957-87-1 N-(t-butyldimethylsilyl)-4-(3-benzyloxycarbonyl-2-hydroxypropyl)-azetidin-2-one 
• 67501-91-1 N-(t-butyldimethylsilyl)-4-(2-acetoxyethyl)-azetidin-2-one 
• 67501-92-2 N-(t-butyldimethylsilyl)-4-(2-hydroxyethyl)-azetidin-2-one 
• 67501-93-3 (4RS)-1-(tert-butyl-dimethylsilyl)-4-(2-oxoethyl)-2-oxoazetidine 

Downstream Products

• 74476-28-1 benzyl 3-oxo-4-[(2RS)-4-oxoazetidin-2-yl]butanoate 
• 74476-32-7 benzyl 3-(p-toluenesulfonyloxy)-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 74476-29-2 4-(3-benzyloxycarbonyl-3-diazo-2-oxopropyl)-azetidin-2-one 
• 74476-30-5 (2S,5S)-3,7-Dioxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 74476-33-8 3-[2-(4-Nitro-benzyloxycarbonylamino)-ethylsulfanyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzyl ester 
• 74476-34-9 1-benzyloxycarbonylmethyl-4-(methoxycarbonylmethyl)-azetidin-2-one 
• 74476-35-0 2-(4-Oxo-azetidin-2-ylmethyl)-malonic acid benzyl ester methyl ester 
• 74476-31-6 2,7-Dioxo-1-aza-bicyclo[3.2.0]heptane-3-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

6- and 6,6-disubstituted-3-substituted-1-azabicyclo(3.2.0)hept-2-en-7-one-2-carboxylic acids

Disclosed are 6- and 6,6-disubstituted-3-substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R1 and R2 are, inter alia, independently selected from the group consisting of hydrogen (both are not hydrog

Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid

Disclosed is a process for preparing 3-substituted-thio-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acids (I) STR1 wherein X is a leaving group such as chloro, bromo, tosyl, mesyl or the like; and R8 is, inter alia, sel

Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Disclosed is a process for preparing 3- and 6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acids: STR1 wherein: X is a leaving group such as chloro, bromo, tosyl, mesyl or the like; and R6, R7 and R8 are, i

6- And 6,6-disubstituted-3-substituted amino-1-azabicyclo-[3.2.0]hept-2-en-7-one-2-carboxylic acid

Disclosed are 6- and 6,6-disubstituted-3-substituted amino-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R1 and R2 are, inter alia, independently selected from the group consisting of hydrogen, substituted a

4-Substituted-2-oxoazetidine compounds

The present invention relates to novel 4-substituted-2-oxoazetidine compounds and to processes for preparing the same. These compounds are useful intermediates for preparing antibiotics having the basic skeleton of Thienamycin.

6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo-?3.2.0!hept-2-en-7-one-2-carboxylic acid

Disclosed are 6-(1'-hydroxyethyl)-3-substituted amino-1-azabicyclo?3.2.0!hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R' and R" are independently selected from H, substituted and unsubstituted alkyl and aralkyl groups, or together form a substitut

3-Substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid

Disclosed are 3-substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R is, inter alia, acyl, alkyl, and aralkyl. Such compounds and their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotic

4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof

This invention relates to novel 4-substituted-2-oxoazetidine compounds and salts thereof, which are useful intermediates in the preparation of antibiotics having the fundamental skeleton of Thienamycin, which compounds are of the formula: STR1 in which R

3-Halo-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid

Disclosed is 3-halo-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid (I): STR1 Such compounds, wherein X is halo, and their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the p

6-(1-Hydroxyethyl)-3-substituted-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid

Disclosed are 6-(1'-hydroxyethyl)-3-substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids(I): STR1 wherein X is halo, oxygen (the 2-3 bond is saturated and the species I exists as the carboxylate salt or ester), or --OR wherein R is, inter ali