74476-30-5

Usage

Molecular structure

Bicyclic structure containing a nitrogen atom and a carboxylic acid functional group

Molecular weight

257.29 g/mol

Appearance

Crystalline solid

Solubility

Soluble in organic solvents such as ethanol, methanol, and acetone

Stability

Stable under normal temperature and pressure conditions

Reactivity

Reacts with other chemical compounds to form esters, amides, and other derivatives

Usage

Commonly used in the pharmaceutical industry as a building block in the synthesis of various drugs and pharmaceuticals

Therapeutic potential

Studied for its potential therapeutic effects in the treatment of various medical conditions.

Upstream product

• 80902-50-7 DL-3-Benzyloxycarbonylamino-glutarsaeuremonobenzylester 
• 80902-54-1 (2-tert-Butoxycarbonylmethyl-4-oxo-azetidin-1-yl)-acetic acid methyl ester 
• 80902-53-0 (1-Methylcarbamoylmethyl-4-oxo-azetidin-2-yl)-acetic acid tert-butyl ester 
• 67501-93-3 (4RS)-1-(tert-butyl-dimethylsilyl)-4-(2-oxoethyl)-2-oxoazetidine 
• 67501-92-2 N-(t-butyldimethylsilyl)-4-(2-hydroxyethyl)-azetidin-2-one 
• 67501-91-1 N-(t-butyldimethylsilyl)-4-(2-acetoxyethyl)-azetidin-2-one 
• 140-11-4 Benzyl acetate 
• 74476-27-0 benzyl 4-[(2RS)-1-(tert-butyl-dimethylsilyl)-4-oxoazetidin-2-yl]-3-oxobutanoate 
• 81957-87-1 N-(t-butyldimethylsilyl)-4-(3-benzyloxycarbonyl-2-hydroxypropyl)-azetidin-2-one 
• 74476-29-2 4-(3-benzyloxycarbonyl-3-diazo-2-oxopropyl)-azetidin-2-one 
• 64066-60-0 4-(2-acetoxyethyl)-2-azetidinone 
• 74476-28-1 benzyl 3-oxo-4-[(2RS)-4-oxoazetidin-2-yl]butanoate 
• 80313-77-5 3-Hydroxy-4-iodo-4-(4-oxo-azetidin-2-yl)-butyric acid benzyl ester 
• 80313-79-7 3-Hydroxy-4-(4-oxo-azetidin-2-yl)-butyric acid benzyl ester 

Downstream Products

• 74476-32-7 benzyl 3-(p-toluenesulfonyloxy)-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 74476-33-8 3-[2-(4-Nitro-benzyloxycarbonylamino)-ethylsulfanyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzyl ester 
• 85756-49-6 benzyl 3-(α-azidoacetoxy)-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 85756-44-1 benzyl 3-acetoxy-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 81946-82-9 Benzyl 3-methoxy-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 81946-71-6 benzyl 3-(p-nitrobenzenesulfonyloxy)-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 81946-70-5 dicyclohexylammonium 1-azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylate 
• 90602-26-9 Benzyl 3-chloro-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 85756-53-2 benzyl 3-(2-azidoethyloxy)-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate 
• 81946-73-8 3-(Diphenoxy-phosphoryloxy)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

6- and 6,6-disubstituted-3-substituted-1-azabicyclo(3.2.0)hept-2-en-7-one-2-carboxylic acids

Disclosed are 6- and 6,6-disubstituted-3-substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R1 and R2 are, inter alia, independently selected from the group consisting of hydrogen (both are not hydrog

Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid

Disclosed is a process for preparing 3-substituted-thio-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acids (I) STR1 wherein X is a leaving group such as chloro, bromo, tosyl, mesyl or the like; and R8 is, inter alia, sel

Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Disclosed is a process for preparing 3- and 6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acids: STR1 wherein: X is a leaving group such as chloro, bromo, tosyl, mesyl or the like; and R6, R7 and R8 are, i

6- And 6,6-disubstituted-3-substituted amino-1-azabicyclo-[3.2.0]hept-2-en-7-one-2-carboxylic acid

Disclosed are 6- and 6,6-disubstituted-3-substituted amino-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R1 and R2 are, inter alia, independently selected from the group consisting of hydrogen, substituted a

6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo-?3.2.0!hept-2-en-7-one-2-carboxylic acid

Disclosed are 6-(1'-hydroxyethyl)-3-substituted amino-1-azabicyclo?3.2.0!hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R' and R" are independently selected from H, substituted and unsubstituted alkyl and aralkyl groups, or together form a substitut

3-Substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid

Disclosed are 3-substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids (I): STR1 wherein R is, inter alia, acyl, alkyl, and aralkyl. Such compounds and their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotic

3-Halo-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid

Disclosed is 3-halo-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid (I): STR1 Such compounds, wherein X is halo, and their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the p

1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid

Disclosed are the pharmaceutically acceptable salt and ester forms of 1-azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid (I): STR1 Such compounds are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceuti

6-(1-Hydroxyethyl)-3-substituted-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid

Disclosed are 6-(1'-hydroxyethyl)-3-substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acids(I): STR1 wherein X is halo, oxygen (the 2-3 bond is saturated and the species I exists as the carboxylate salt or ester), or --OR wherein R is, inter ali

A FACILE SYNTHESIS OF BENZYL 3,7-DIOXO-1-AZABICYCLOHEPTANE-2-CARBOXYLATE. A POTENTIAL PRECURSOR OF THIENAMYCIN AND CLAVULANIC ACID ANALOGS

A novel, high yield synthesis of the 1-carbapenam ring system 3 is described in which the entire carbon framework is introduced in a single step from simple precursors.