74479-32-6Relevant academic research and scientific papers
Manganese-Catalyzed α-Olefination of Nitriles with Secondary Alcohols
Balaraman, Ekambaram,Landge, Vinod G.,Subaramanian, Murugan,Yadav, Vinita
, p. 947 - 954 (2020/01/13)
An expedient catalytic approach for α-olefination of nitriles using secondary alcohols with the liberation of molecular hydrogen and water as the only byproducts is reported. This reaction is catalyzed by a molecularly defined manganese(I) pincer complex and operates in the absence of any hydrogen acceptors. A broad range of substrates including cyclic, acyclic, and benzylic alcohols, as well as various nitrile derivatives, such as arylmethyl and heteroarylmethyl nitriles, are employed in the reaction to provide a diverse range of α-vinyl nitriles in good to excellent yields. Mechanistic studies showed that the reaction proceeds via dehydrogenative pathway and the activation of α(C-H) bond of the alcohol is the rate-determining step.
SYNCHRONOUS ELIMINATION OF THE NITRO AND ESTER GROUPS OR THE NITRO AND KETO GROUPS VIA ONE ELECTRON TRANSFER REACTION
Tamura, Rui,Nakatsuka, Tamon,Ono, Noboru,Kaji, Aritsune
, p. 281 - 282 (2007/10/02)
The nitro and ester groups are eliminated from α-cyano-β-nitroesters (1) on treatment with one electron transfer reagents.Similarly, the nitro and acetyl groups are eliminated from α-acetyl-β-nitroesters (2) or α-acetyl-β-nitroketones (3).
