74479-45-1 Usage
Uses
Used in Pharmaceutical Industry:
9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid methyl ester is used as an intermediate in the synthesis of Acitretin for the treatment of various skin disorders, such as psoriasis, atopic dermatitis, and other keratinization disorders. Its retinoid activity helps regulate cell growth, differentiation, and inflammation, making it an effective therapeutic agent in dermatological treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 74479-45-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,7 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 74479-45:
(7*7)+(6*4)+(5*4)+(4*7)+(3*9)+(2*4)+(1*5)=161
161 % 10 = 1
So 74479-45-1 is a valid CAS Registry Number.
74479-45-1Relevant academic research and scientific papers
STEREOSELECTIVE SYNTHESIS OF THE AROMATIC ANALOGS OF RETINAL AND RETONOIC ACID
Makin, S. M.,Mikerin, I. E.,Shavrygina, O. A.,Lanina, T. I.
, p. 710 - 715 (2007/10/02)
The stereoselective synthesis of 9-aryl-4-carboxy-3,7-dimethyl-2Z,4Z,6E,8E-nonatetraenoic acids and 9-aryl-3,7-dimethyl-2Z,4E,6E,8E-nonatetraenoic acids was realized.The latter isomerize readily and with good yields under the influence of iodine additions to 9-aryl-3,7-dimethyl-2E,4E,6E,8E-nonatetraenoic acids.The transition from the isomeric 9-aryl-3,7-dimethyl-2,4,6,8-nonatetraenoic acids to the corresponding isomeric 9-aryl-3,7-dimethyl-2Z,4E,6E,8E-nonatetraenals and 9-aryl-3,7-dimethyl-2E,4E,6E,8E-nonatetraenals was realized.
