74479-45-1

Basic information

• Product Name: 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid methyl ester
• CAS NO: 74479-45-1
• Molecular Weight: 340.463
• Mol File: 74479-45-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid methyl ester(74479-45-1)
• EPA Substance Registry System: 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid methyl ester(74479-45-1)

Safety Data

• Hazardous Substances Data: 74479-45-1(Hazardous Substances Data)

Usage

Uses

Acitretin Methyl Ester is an intermediate of Acitretin (A189900), which is a synthetic retinoid which is the major metabolite of etretinate (E938000).

Upstream product

• 186581-53-3 diazomethane 
• 54757-46-9 acitretin 
• 131980-79-5 methyl ethyl β-methylglutaconate 
• 69877-38-9 5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-2(E),4(E)-pentadien-1-al 
• 69427-46-9 13-cis-Acitretin 
• 127613-71-2 9-(4-methoxy-2,3,6-trimethylphenyl)-4-carboxy-3,7-dimethyl-2Z,4Z,6E,8E-nonatetraenoic acid 

Downstream Products

• 61630-49-7 (2E,4E,6E,8E)-9-(4-methoxyl-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraen-1-ol 
• 58508-38-6 (2E,4E,6E,8E)-9-(4-methoxyl-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenal 

Relevant articles and documents

STEREOSELECTIVE SYNTHESIS OF THE AROMATIC ANALOGS OF RETINAL AND RETONOIC ACID

The stereoselective synthesis of 9-aryl-4-carboxy-3,7-dimethyl-2Z,4Z,6E,8E-nonatetraenoic acids and 9-aryl-3,7-dimethyl-2Z,4E,6E,8E-nonatetraenoic acids was realized.The latter isomerize readily and with good yields under the influence of iodine additions to 9-aryl-3,7-dimethyl-2E,4E,6E,8E-nonatetraenoic acids.The transition from the isomeric 9-aryl-3,7-dimethyl-2,4,6,8-nonatetraenoic acids to the corresponding isomeric 9-aryl-3,7-dimethyl-2Z,4E,6E,8E-nonatetraenals and 9-aryl-3,7-dimethyl-2E,4E,6E,8E-nonatetraenals was realized.