74480-77-6Relevant academic research and scientific papers
The first de novo designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase
Heikkilae, Timo,Thirumalairajan, Srinath,Davies, Matthew,Parsons, Mark R.,McConkey, A. Glenn,Fishwick, Colin W. G.,Johnson, A. Peter
, p. 88 - 92 (2007/10/03)
The de novo molecular design program SPROUT has been applied to the X-ray crystal structures of Plasmodium and human dihydroorotate dehydrogenase, respectively. The resulting design templates were used to prepare a series of molecules which, in keeping wi
Photocyclisation of Enamides. Part 14. Substituent Effects in the Photocyclisation of N-α,β-Unsaturated Acylanilides.
Ninomiya, Ichiya,Kiguchi, Toshiko,Yamauchi, Sadami,Naito, Takeaki
, p. 197 - 202 (2007/10/02)
Irradiation of N-α,β-unsaturated acylanilides having various substituents on the benzene ring yielded a mixture of cis- and trans-octahydrophenanthridones (3a-f) and dihydroquinolones (5a, e, and f).The N-alkylanilides (
