7449-47-0Relevant academic research and scientific papers
Sulfonamide-Linked ciprofloxacin, sulfadiazine and amantadine derivatives as a novel class of inhibitors of jack bean urease; synthesis, kinetic mechanism and molecular docking
Channar, Pervaiz Ali,Saeed, Aamer,Albericio, Fernando,Larik, Fayaz Ali,Abbas, Qamar,Hassan, Mubashir,Raza, Hussain,Seo, Sung-Yum
, (2017/08/29)
Sulfonamide derivatives serve as an important building blocks in the drug design discovery and development (4D) process. Ciprofloxacin-, sulfadiazine- and amantadine-based sulfonamides were synthesized as potent inhibitors of jack bean urease and free rad
Synthesis of some p-toluenesulfonyl-hydrazinothiazoles and hydrazino-bis-thiazoles and their anticancer activity
Zaharia, Valentin,Ignat, Adriana,Palibroda, Nicolae,Ngameni, Bathélémy,Kuete, Victor,Fokunang, Charles N.,Moungang, Marlyse L.,Ngadjui, Bonaventure T.
experimental part, p. 5080 - 5085 (2010/12/24)
A series of novel p-toluenesulfonyl-hydrazinothiazoles and hydrazino-bis-thiazoles derivatives (2a-f, 3a-f and 5-8) were synthesized by initial condensation of p-toluenesulfonylthiosemicarbazide 1 with a series of α-halogenocarbonyls in acetone or dimethy
CARBONIC ANHYDRASE INHIBITORS. 9. INHIBITORS WITH MODIFIED SULFONAMIDO GROUPS AND THEIR INTERACTION WITH THE ZINC ENZYME
Supuran, Claudiu T.,Banciu, Mircea D.
, p. 1345 - 1354 (2007/10/03)
A number of 20 compounds, containing modified sulfonamido groups were prepared and tested as carbonic anhydrase inhibitors on the bovine enzyme. Novel classes of inhibitors were evidenced, and a new mode of binding for bidentate inhibitors was proposed, both for the native and Co(II) substituted enzyme.
