74495-79-7

Upstream product

• 135-88-6 N-Phenyl-2-naphthylamine 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 463-51-4 Ketene 

Downstream Products

• 135-88-6 N-Phenyl-2-naphthylamine 
• 290310-56-4 [(E)-1-Chloro-3-dimethylamino-prop-2-en-(Z)-ylidene]-naphthalen-2-yl-phenyl-ammonium 
• 1301721-56-1 9-(methoxycarbonyl)-7-phenyl-benzo[f]thieno[2,3-b]quinolinium perchlorate 
• 1379764-28-9 9-methoxycarbonyl-7-phenyl-4,9-dihydrobenzo[f]thieno[2,3-b]quinoline 
• 290310-57-5 1-chloro-3-dimethylamino-1-(N-(2-naphthyl)-N-phenyl)propeniminium perchlorate 
• 612-94-2 2-phenylnaphthalene 
• 101731-88-8 6-(N-acetyl-anilino)-naphthalene-1-sulfonic acid amide 
• 349533-49-9 5-(naphthalen-2-yl-phenyl-amino)-thiophene-2-carboxylic acid 
• 1065106-73-1 methyl 2-[(naphthalen-2-yl)(phenyl)amino]thiophene-5-carboxylate 
• 349533-44-4 naphthalen-2-yl-phenyl-thiophen-2-yl-amine 
• 110513-28-5 6-(N-acetyl-anilino)-naphthalene-1-sulfonyl chloride 

Relevant academic research and scientific papers

Nickel-Catalyzed Kumada Coupling of Boc-Activated Aromatic Amines via Nondirected Selective Aryl C-N Bond Cleavage

A nickel-catalyzed Kumada coupling of aniline derivatives was developed by selective cleavage of aryl C-N bonds under mild reaction conditions. Without preinstallation of an ortho directing group on anilines, the cross-coupling reactions of Boc-protected aromatic amines with aryl Grignard reagents afforded unsymmetric biaryls. Mechanistic studies by DFT calculations revealed that the nickel-mediated C-N bond cleavage is the rate-limiting step.

Hollow fiber liquid-phase microextraction with in situ derivatization combined with gas chromatography-mass spectrometry for the determination of root exudate phenylamine compounds in hot pepper (Capsicum annuum L.)

Hollow fiber liquid-phase microextraction (HF-LPME) with derivatization was developed for the determination of three root exudate phenylamine compounds in hot pepper (Capsicum annuum L.) by gas chromatography-mass spectrometry (GC-MS). The performance and applicability of the proposed procedure were evaluated through the extraction of 1-naphthylamine (1-NA), diphenylamine (DPA), and N-phenyl-2- naphthaleneamine (N-P-2-NA) in a recirculating hydroponic solution of hot pepper. Parameters affecting the extraction efficiency were investigated. The calibration curves showed a good linearity in the range of 0.1-10 μg mL-1. The limits of detection (S/N = 3) for the three compounds were 0.096, 0.074, and 0.057 μg mL-1, respectively. The enrichment factors reached 174, 196, and 230 at the concentration of 5 μg mL -1, and relative standard deviations (RSD) of 9.5, 8.6, and 7.8% and 8.4, 7.6, and 6.2% were obtained at concentrations of 2 and 5 μg mL -1 for 1-NA, DPA, and N-P-2-NA, respectively. Recoveries ranging from 90.2 to 96.1% and RSDs below 9.1% were obtained when HF-LPME with in situ derivatization was applied to determine root exudate 1-NA, DPA, and N-P-2-NA after 15 and 30 days of culture solution, respectively.