74498-81-0Relevant articles and documents
Inhibitors of Sterol Biosynthesis. Synthesis of 9α-Fluoro-3β-hydroxy-5α-cholest-8(14)-en-15-one and Related Compounds
Parish, Edward J.,Schroepfer, George J.
, p. 4034 - 4037 (1980)
9α-Fluoro-3β-hydroxy-5α-cholest-8(14)-en-15-one has been prepared in 90percent yield by treatment of 3β,9α-dihydroxy-5α-cholest-8(14)-en-15-one with HF-pyridine.These two compounds are potent inhibitors of sterol biosynthesis in animal cells in culture an