745020-65-9Relevant academic research and scientific papers
Selective glucose sensing utilizing complexation with fluorescent boronic acid on polycation
Kanekiyo, Yasumasa,Tao, Hiroaki
, p. 196 - 197 (2005)
A novel sensing system for selective glucose detection has been established based on the 1:2 complex formation between glucose and fluorescent boronic acid in the presence of polycation which results in the emergence of excimer emission. Copyright
Stepwise chemical reaction strategy for highly sensitive electrochemiluminescent detection of dopamine
Zhang, Lei,Cheng, Yan,Lei, Jianping,Liu, Yueting,Hao, Qing,Ju, Huangxian
, p. 8001 - 8007 (2013)
A stepwise chemical reaction strategy based on the specific recognition of boronic acid to diol, and N-hydroxysuccinimide (NHS) ester to amine group, was designed to construct a signal on electrochemiluminescence (ECL) platform for highly sensitive detection of dopamine. A boronic acid-functionalized pyrene probe was synthesized and was self-assembled on the sidewalls of carbon nanotubes via π-π stacking interactions as capture probes on a glassy carbon electrode. Meanwhile, 3,3′-dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP)-functionalized CdTe quantum dots (QDs) were designed as signal probes and characterized with transmission electron microscopy and spectroscopic techniques. Upon stepwise chemical reaction of dopamine with boronic acid and then DSP-QDs, the QDs were captured on the electrode as ECL emitters for signal readout, leading to an ultralow background signal. By using O2 as an endogenous coreactant, the signal on ECL method was employed to quantify the concentration of dopamine from 50 pM to 10 nM with a detection limit of 26 pM. Moreover, the stepwise chemical reaction-based biosensor showed high specificity against cerebral interference and was successfully applied in the detection of dopamine in cerebrospinal fluid samples. The stepwise chemical reaction strategy should be a new concept for the design of highly selective analytical methods for the detection of small biomolecules.
Fluorescence detection of ATP based on the ATP-mediated aggregation of pyrene-appended boronic acid on a polycation
Kanekiyo, Yasumasa,Naganawa, Ryuichi,Tao, Hiroaki
, p. 1006 - 1007 (2004)
A novel fluorescent sensing system for ATP has been created utilizing the ATP-mediated aggregation process of pyrene-appended boronic acid on a polycation.
