745050-30-0Relevant academic research and scientific papers
Racemic and chiral sulfoxides as potential prodrugs of the COX-2 inhibitors Vioxx and Arcoxia
Caturla, Francisco,Amat, Merce,Reinoso, Raquel F.,Cordoba, Monica,Warrellow, Graham
, p. 3209 - 3212 (2007/10/03)
The preparation of the sulfoxide analogues 2 and 4, and their enantiomeric pure forms is discussed as well as their potential to act as prodrugs to the potent and selective sulfone-containing COX-2 inhibitors rofecoxib and etoricoxib. Sulfoxides 2 and 4 w
2,3'-BIPYRIDINES DERIVATIVES AS SELECTIVE COX-2 INHIBITORS
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Page 11, (2008/06/13)
The present invention relates to 2,3'-bipyridines of formula (I). Processes for their preparation, pharmaceutical compositions containing them, and their medical uses.
