745053-64-9

Basic information

• Product Name: 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE
• Synonyms: 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE;2-Amine-5-Fluorothiazol HCL;2-Amino-5-fluoro-1,3-thiazole hydrochloride;5-Fluoro-1,3-thiazol-2-amine hydrochloride;2-AMino-5-fluorothiazole HCl;5-Fluorothiazole-2-aMine hydrochloride;5-Fluorothiazol-2-aMine HCl;2-ThiazolaMine, 5-fluoro-, Monohydrochloride
• CAS NO: 745053-64-9
• Molecular Formula: C₃H₃FN₂S*ClH
• Molecular Weight: 154.59
• Mol File: 745053-64-9.mol
• Article Data: 9

Chemical Properties

• Melting Point: 138-143°C
• Boiling Point: 221.8°C at 760 mmHg
• Flash Point: 88°C
• Appearance: /
• Vapor Pressure: 0.105mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE(745053-64-9)
• EPA Substance Registry System: 5-FLUOROTHIAZOL-2-AMINE HYDROCHLORIDE(745053-64-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 745053-64-9(Hazardous Substances Data)

Usage

Uses

5-Fluorothiazol-2-amine Hydrochloride can be used as anti-tumor agents.

InChI:InChI=1/C3H3FN2S.ClH/c4-2-1-6-3(5)7-2;/h1H,(H2,5,6);1H

Upstream product

• 731018-54-5 2-(tert-butoxycarbonyl)amino-5-fluorothiazole 
• 876379-99-6 2-acetamido-5-fluorothiazole 
• 40283-46-3 2-aminothiazole-5-carboxylic acid 
• 745053-67-2 N-(5-fluorothiazol-2-yl)-2,2,2-trifluoroacetamide 

Downstream Products

• 745051-61-0 PSN-GK1 
• 1454666-63-7 N-(5-fluorothiazol-2-yl)-5-(2-(5-methyl-1H-imidazol-1-yl)-4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-sulfonamide 
• 1454666-62-6 N-(5-fluorothiazol-2-yl)-5-(2-(4-methyl-1H-imidazol-1-yl)-4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-sulfonamide 
• 1454666-61-5 N-(5-fluorothiazol-2-yl)-5-(2-(4-methylpiperazin-1-yl)-4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-sulfonamide 
• 1282521-02-1 3-acetoxymethyl-5-(2-methoxy-(1S)-methyl-ethoxy)-N-(5-fluorothiazol-2-yl)-benzamide 
• 1325706-40-8 3-(6-cyclopropanesulfonylpyridin-3-yloxy)-N-(5-fluorothiazol-2-yI)-5-isopropoxybenzamide 
• 1204244-03-0 (4-fluorophenyl)(4-(5-fluorothiazol-2-ylamino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)methanone 
• 1039016-49-3 C₁₈H₁₉FN₄O₄S₂ 
• 64588-82-5 5-fluoro-1,3-thiazol-2-amine 

Relevant articles and documents

METHOD OF MAKING AZAINDAZOLE DERIVATIVES

Disclosed are methods, reagents, and intermediates useful for making azaindazole derivatives, which may be used to modulate Glucokinase. The disclosed methods and materials are generally useful for making halo-esters and sulfonyl-substituted compounds.

HYDRAZONE DERIVATIVE

A hydrazone derivative of formula [I]: wherein Ring A is aryl or heteroaryl, Ring T is heteroaryl or heterocycle, R1 and R2 are independently hydrogen atom, halogen atom, cycloalkylsulfonyl, etc., R3 and R4 comb

FLUORINATION PROCESS OF PROTECTED AMINOTHIAZOLE

A process for the production of fluorinated compound formula (I) comprising fluorination of a protected aminothiazole. Compounds formula (I) are useful in the preparation of activators of glucokinase.