745079-30-5

Upstream product

• 637338-23-9 (4S)-4-phenyl-N-[(4S)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-4,5-dihydro-1,3-oxazol-2-amine 
• 74-88-4 methyl iodide 
• 165035-65-4 (S)-2-amino-4-phenyl-4,5-dihydro-1,3-oxazole 
• 119109-55-6 (4S)-2-ethoxy-4-phenyl-4,5-dihydro-1,3-oxazole 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 
• 20989-17-7 (2S)-2-phenylglycinol 

Relevant academic research and scientific papers

The role of binding constants in the efficiency of chiral catalysts immobilized by electrostatic interactions: The case of azabis(oxazoline)-copper complexes

As shown by theoretical calculations, azabis(oxazoline)-copper complexes are considerably more stable than the analogous bis(oxazoline)-copper complexes. This enhanced stability allows them to be efficiently immobilized by means of electrostatic interactions to different anionic supports, such as clays and nafion-silica nanocomposites, without the loss of a ligand, as is observed for bis(oxazolines). As a result, enantioselectivities of around 90% ee are obtained in the cyclopropanation reaction between styrene and ethyl diazoacetate. Moreover, the solid catalyst is easily recoverable.