74531-15-0

Basic information

• Product Name: 2-Thiazolecarboxaldehyde, 4,5-dimethyl- (6CI, 9CI)
• Synonyms: 2-Thiazolecarboxaldehyde, 4,5-dimethyl- (6CI, 9CI);4,5-DiMethylthiazole-2-carbaldehyde;2-Thiazolecarboxaldehyde, 4,5-diMethyl-;4,5-Dimethyl-1,3-thiazole-2-carboxaldehyde;4,5-Dimethylthiazole-2-carboxaldehyde;4,5-Dimethyl-2-formylthiazole;4,5-Dimethyl-2-thiazolecarbaldehyde
• CAS NO: 74531-15-0
• Molecular Formula: C₆H₇NOS
• Molecular Weight: 141.19
• Product Categories: ALDEHYDE
• Mol File: 74531-15-0.mol

Chemical Properties

• Melting Point: 33-39°C
• Boiling Point: 260℃
• Flash Point: 111℃
• Appearance: /
• Density: 1.213
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Thiazolecarboxaldehyde, 4,5-dimethyl- (6CI, 9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolecarboxaldehyde, 4,5-dimethyl- (6CI, 9CI)(74531-15-0)
• EPA Substance Registry System: 2-Thiazolecarboxaldehyde, 4,5-dimethyl- (6CI, 9CI)(74531-15-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 74531-15-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Thiazolecarboxaldehyde, 4,5-dimethyl(6CI, 9CI) is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure contributes to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Thiazolecarboxaldehyde, 4,5-dimethyl(6CI, 9CI) serves as a vital component in the production of pesticides and other agrochemicals. Its incorporation aids in enhancing the effectiveness of these products in agricultural practices.
Used in Perfume Industry:
2-Thiazolecarboxaldehyde, 4,5-dimethyl(6CI, 9CI) is utilized as a fragrance ingredient in the perfume industry. Its distinct aromatic properties allow it to contribute to the creation of unique and appealing scents in perfumes and other fragranced products.
Used in Food Industry:
As a flavoring agent, 2-Thiazolecarboxaldehyde, 4,5-dimethyl(6CI, 9CI) is employed in the food industry to impart specific tastes and aromas to various food products, enhancing their overall sensory appeal.

Upstream product

• 2289-75-0 4,5-dimethyl-1,3-thiazole-2-amine 
• 75-17-2 formaldoxime 
• 3581-91-7 4,5-Dimethylthiazole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 933751-02-1 N-[(4,5-dimethyl-1,3-thiazol-2-yl)methyl]-N-methylamine 
• 99839-16-4 (4,5-dimethyl-1,3-thiazol-2-yl)methanol 
• 89601-18-3 (4,5-dimethylthiazol-2-yl)methanamine 

Relevant articles and documents

SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS

The present invention is directed to substituted pyridizinone compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS

The present invention is directed to substituted pyridizinone compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

1-(DIHYDRONAPHTHALENYL)PYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

Provided are 1-(dihydronaphthalenyl)pyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy for the treatment of obesity and diabetes.

TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. (I)

New 1,2,4-triazine derivatives and biological applications thereof

The invention relates to new 1,2,4-triazine derivatives of formula (I): wherein A, B, R2 and Y are defined in the application, their preparation and intermediates, their use as drugs and pharmaceutical compositions and associations containing them. The compounds of formula (I) are capable of inhibiting bacterial heptose synthesis.