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4-(1-hydroxy-2-oxo-2-phenylethyl)benzonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

74552-53-7

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74552-53-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 74552-53-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,5 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74552-53:
(7*7)+(6*4)+(5*5)+(4*5)+(3*2)+(2*5)+(1*3)=137
137 % 10 = 7
So 74552-53-7 is a valid CAS Registry Number.

74552-53-7Downstream Products

74552-53-7Relevant academic research and scientific papers

Visible Light Enabled Formal Cross Silyl Benzoin Reaction as an Access to α-Hydroxyketones

Ma, Liyao,Yu, Yinghua,Xin, Luoting,Zhu, Lei,Xia, Jiajin,Ou, Pengcheng,Huang, Xueliang

supporting information, p. 2573 - 2577 (2021/04/05)

In this work, a visible-light enabled coupling of acylsilanes with aldehydes to give a range of cross-benzoin type products α-hydroxyketones is described. The reaction could proceed at ambient temperature, with the irradiation of low energy visible light, and without addition of photosensitizer or any other additives. (Figure presented.).

Reductive Coupling of Benzoyl Cyanide and Carbonyl Compounds by Aqueous Ti(III) Ions. A New Convenient and Selective Access to the Less Stable Mixed Benzoins

Clerici, Angelo,Porta, Ombretta

, p. 2889 - 2893 (2007/10/02)

The reactive species formed by the Ti(III) ion reduction of benzoyl cyanide (1) adds to the C-atom of carbonyl compounds 2 under simple experimental conditions.The intermediate 1,2-diols 3 are smoothly converted, without isolation, into the less thermodynamically stable mixed benzoins 4, which are not accessible by the classical benzoin condensation.The possible mechanisms involved in the reaction are discussed.

α-HETEROSUBSTITUTED PHOSPHONATE CARBANIONS IX : DIETHYL 1-PHENYL-1-TRIMETHYLSILOXYMETHANE PHOSPHONATE AS AN ACYL ANION EQUIVALENT; A NOVEL METHOD FOR THE PREPARATION OF α-HYDROXYKETONES.

Koenigkramer, Rusty E.,Zimmer, Hans

, p. 1017 - 1020 (2007/10/02)

Diethyl 1-phenyl-1-trimethylsiloxymethane phosphonate carbanion was found to react as an effective acyl anion equivalent in the preparation of α-hydroxy ketones from aliphatic and aromatic aldehydes and ketones.A 1,4-oxygen-oxygen silicon migration was also observed.

α-Heterosubstituted Phosphonate Carbanions. 11. Benzoins via an Acyl Anion Equivalent. Novel One-Pot Preparation of Benzofurans via Benzoins Using Hydriodic Acid

Koenigkramer, Rusty E.,Zimmer, Hans

, p. 3994 - 3998 (2007/10/02)

Diethyl 1-(trimethylsiloxy)-1-phenylmethanephosphonate carbanion 2 is introduced as a novel acyl anion equivalent.When 2 reacts with aldehydes or ketones, a 1,4 oxygen-oxygen silicon migration with subsequent loss of diethyl lithium phosphite is observed.An efficient method utilizing 2 for the preparation of otherwise difficultly obtainable substituted benzoins is presented.Also a novel one-pot method which offers a facile entry into the 2-phenylbenzofuran ring system from 2 via benzoin intermediates using hydriodic acid was developed.

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