74571-98-5

Basic information

• Product Name: (R)-4-benzyl-3-MethylMorpholine
• Synonyms: (R)-4-benzyl-3-MethylMorpholine;Morpholine, 3-Methyl-4-(phenylMethyl)-, (3R)-
• CAS NO: 74571-98-5
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.26948
• Mol File: 74571-98-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 265.5±20.0 °C(Predicted)
• Appearance: /
• Density: 1.023±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.66±0.40(Predicted)
• CAS DataBase Reference: (R)-4-benzyl-3-MethylMorpholine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-benzyl-3-MethylMorpholine(74571-98-5)
• EPA Substance Registry System: (R)-4-benzyl-3-MethylMorpholine(74571-98-5)

Safety Data

• Hazardous Substances Data: 74571-98-5(Hazardous Substances Data)

Usage

General Description

(R)-4-Benzyl-3-methylmorpholine is a chemical compound with a molecular formula of C12H17NO. It is a morpholine derivative, which is a type of heterocyclic organic compound. This particular compound is a chiral molecule, with the (R)-enantiomer being the active form. It is commonly used as a synthetic intermediate in the production of pharmaceuticals and agrochemicals. The morpholine ring confers unique properties to the compound, making it useful in various applications such as drug development and agricultural products. Its structure and reactivity make it a versatile building block in organic synthesis, enabling the production of a wide range of valuable compounds.

Upstream product

• 697763-59-0 (R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-propan-1-ol 
• 100-52-7 benzaldehyde 
• 120800-86-4 (5R)-5-methyl-4-(phenylmethyl)-3-morpholinone 
• 51070-67-8 2-bromo-1-(2-chloro-ethoxy)-propane 
• 100-46-9 benzylamine 
• 74609-49-7 (2R)-2-[(phenylmethyl)amino]-1-propanol 
• 74571-95-2 (R)-2-[Benzyl-(2-hydroxy-ethyl)-amino]-propan-1-ol 
• 127536-05-4 (2-Allyloxy-ethyl)-benzyl-amine 

Downstream Products

• 1227911-27-4 4-{2-amino-6-[(3R)-3-methyl-4-morpholinyl]-4-pyrimidinyl}-2-fluorobenzonitrile 
• 953780-78-4 (3R)-3-methylmorpholine hydrochloride 
• 74572-04-6 (3R)-3-methylmorpholine 

Relevant articles and documents

A N-heterocyclic carbene (NHC) platinum complex as pre-catalyst for the intramolecular hydroamination of olefins with secondary alkylamines and oxidative amination of ω-alkenic amines

A N-heterocyclic carbene (NHC) platinum complex 3 prepared from BINAM was found to be a highly effective pre-catalyst for the intramolecular hydroamination of olefins with secondary alkylamines to give the corresponding intramolecular hydroamination products in excellent yields. The substrate scope has been carefully examined and the plausible reaction mechanism has been also proposed.

CHEMICAL COMPOUNDS

The invention is directed to 6-(4-pyι?midinyl)-1 H-indazole derivatives. Specifically, the invention is directed to compounds according to Formula (I) wherein R1 - R4 are defined herein. The compounds of the invention are inhibitors of PDK1 and can be useful in the treatment of immune and metabolic diseases and disorders characterized by constitutively activated ACG kinases such as cancer and more specifically cancers of the breast, colon, and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting PDK1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS

Compounds of formulae I, II and III: are disclosed as 5-HT3 inhibitors. The compounds are useful in treating CINV, IBS-D and other diseases and conditions.