74578-33-9Relevant academic research and scientific papers
COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS
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Page/Page column 117-118, (2016/05/24)
Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein (II), A, R1, R2, R3a, R4a, R4b, R5, R7a, and R7b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.
Functionalisation of Saturated Hydrocarbons. Part 6. Selective Oxidation of Steroids and Related Compounds
Barton, Derek H. R.,Boivin, Jean,Hill, Christopher H.
, p. 1797 - 1804 (2007/10/02)
The oxidation of a series of steroids by the Gif system gives, almost without exception, the 20-ketone as major isolated product.The side-chain cleavage is made more selective by modification of rings A or B.The oxidation of oleana-1,12-diene-3,11-dione has also been studied and the two principal products have been identified.
Mercapto steroids in protection against mercury and lead poisoning
Blickenstaff,Cox,Foster,Roberts,Steinrauf
, p. 556 - 558 (2007/10/02)
When thiocholesterol is administered as liposomes, it provides significant protection against methylmercuric chloride in mice when given in three intraperitoneal injections, 0.5 hr before and 2 and 8 hr after the methylmercuric chloride. Thiositosterol, 5
