745818-75-1

Upstream product

• 19790-60-4 3-Benzyloxypropanal 
• 745818-72-8 ethyl 7-(benzyloxy)-5-hydroxy-2,2-dimethyl-3-oxoheptanoate 
• 597-04-6 ethyl 2,2-dimethyl-3-oxobutanoate 
• 745818-73-9 (E)-ethyl 7-(benzyloxy)-2,2-dimethyl-3-oxohept-4-enoate 

Downstream Products

• 745818-78-4 (4R,5S)-5-[(1S)-3-(benzyloxy)-1-methoxypropyl]-4-hydroxy-3,3-dimethyldihydrofuran-2(3H)-one 
• 745818-77-3 (5R)-5-[(1S)-3-(benzyloxy)-1-methoxypropyl]-3,3-dimethylfuran-2,4(3H,5H)-dione 

Relevant academic research and scientific papers

Stereoselective synthesis of the C9-C19 lactone-dipropionate fragment of calyculin C

A highly diastereoselective synthesis of the title fragment of calyculin C has been developed based on an internal asymmetric induction between a chiral aldehyde and Z-crotyl trifluorosilane.

Studies towards the synthesis of the C(9)-C(20) lactone-dipropionate fragment of calyculin C

In this paper we describe the synthesis of a diastereomer of the C(9)-C(20) dipropionate-lactone fragment of Calyculin C. A short and enantioselective synthesis of the key intermediate 2 has been developed. This intermediate will play a critical role also