74582-94-8

Upstream product

• 106-25-2 Nerol 
• 151-50-8 potassium cyanide 
• 7677-24-9 trimethylsilyl cyanide 
• 85217-73-8 (Z)-3,7-dimethylocta-2,6-dien-1-yl methyl carbonate 
• 85217-72-7 geranyl methyl carbonate 
• 19451-55-9 Neryl diphenyl phosphate 
• 143-33-9 sodium cyanide 
• 106-26-3 cis-3,7-dimethyl-2,6-octadienal 

Relevant academic research and scientific papers

Cyanation of Allylic Carbonates and Acetates Using Trimethylsilyl Cyanide Catalyzed by Palladium Complex

Allylic carbonates and acetates are cyanated with trimethylsilyl cyanide in the presence of a catalytic amount (5 mol percent based on the allylic substrates) od Pd(PPh3)4 or Pd(CO)(PPh3)3 in THF under reflux to afford β,γ-unsaturated nitriles in high yields.

Cyano Phosphate: An Efficient Intermediate for the Chemoselective Conversion of Carbonyl Compounds to Nitriles

Cyanohydrin diethyl phosphates, readily obtained from various ketones and aldehydes by reaction with diethyl phosphorocyanidate and lithium cyanide, reacted chemoselectively with samarium(II) iodide in THF to give the corresponding nitriles in excellent yields.This method was also found applicable to α,β-unsaturated carbonyl compounds via cyano phosphates to give β,γ-unsaturated nitriles, not obtainable by standard methods, without isomerization of the double bonds.

Reaction of Allyl Diphenyl Phosphates with Soft Bases

The title phosphates were found to react with a variety of soft bases to give nucleophilic substitution products in high yields.The reaction proceeded regiospecifically under mild reaction conditions with preservation of the double bond geometry.