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3-IODO-4-METHOXYANILINE, also known as 3-iodo-4-methoxyaniline, is a chemical compound with the molecular formula C7H8INO. It belongs to the class of organic compounds known as anilines, which are aromatic amines derived from benzene. This chemical is a pink to brown solid at room temperature and is commonly used as an intermediate in the production of dyes, pharmaceuticals, and other organic compounds. It is also used in the synthesis of fine chemicals and as a building block in the creation of various complex organic molecules. 3-Iodo-4-methoxyaniline is known to have some potential health hazards and should be handled with caution in a controlled laboratory setting.

74587-12-5

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74587-12-5 Usage

Uses

Used in Dye Production:
3-IODO-4-METHOXYANILINE is used as an intermediate for the production of dyes, contributing to the synthesis of various colorants used in different industries.
Used in Pharmaceutical Industry:
3-IODO-4-METHOXYANILINE is used as a building block in the synthesis of pharmaceuticals, aiding in the development of new drugs and medicinal compounds.
Used in Organic Compounds Synthesis:
3-IODO-4-METHOXYANILINE is used as a precursor in the synthesis of fine chemicals, playing a crucial role in the creation of complex organic molecules for various applications.
Used in Research and Development:
3-IODO-4-METHOXYANILINE is used as a research compound in the development of new chemical processes and the exploration of its potential applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 74587-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,8 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 74587-12:
(7*7)+(6*4)+(5*5)+(4*8)+(3*7)+(2*1)+(1*2)=155
155 % 10 = 5
So 74587-12-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H8INO/c1-10-7-3-2-5(9)4-6(7)8/h2-4H,9H2,1H3

74587-12-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Iodo-4-methoxyaniline

1.2 Other means of identification

Product number -
Other names 3-IODO-4-METHOXYANILINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:74587-12-5 SDS

74587-12-5Relevant academic research and scientific papers

AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS, SALTS THEREOF, AND METHODS OF SYNTHESIS THEREOF

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Paragraph 01611, (2019/05/10)

The present disclosure relates to amine-substituted heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., cancer) by administering an amine-substituted heterocyclic heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.

AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF

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Paragraph 0421-0424, (2018/07/29)

The present disclosure relates to amine-substituted heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., cancer) via inhibition of a methyltransfera

HETEROCYCLIC COMPOUNDS

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Paragraph 0303, (2016/12/26)

The present invention provides a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof has an BET family protein inhibitory action, and is useful as an agent for the prophylaxis or treatment of autoimmune diseases and/or inflammatory diseases (e.g., rheumatoid arthritis, multiple sclerosis, idiopathic pulmonary fibrosis, psoriasis, atopic dermatitis, inflammatory bowel disease, Sjogren's syndrome, Behcet's disease, systemic lupus erythematosus etc.), cancer and the like.

OXAZOLO[5,4-C]QUINOLIN-2-ONE COMPOUNDS AS BROMODOMAIN INHIBITORS

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Paragraph 00230, (2014/10/04)

The present invention relates to compounds useful as bromodomain inhibitors. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compounds and compositions in the treatment of various diseases and disorders.

Electrochemical C-H amination: Synthesis of aromatic primary amines via N -arylpyridinium ions

Morofuji, Tatsuya,Shimizu, Akihiro,Yoshida, Jun-Ichi

supporting information, p. 5000 - 5003 (2013/05/22)

We have developed a new method for C-H amination of aromatic compounds based on electrochemical oxidation of aromatic compounds in the presence of pyridine followed by the reaction of the resulting N-arylpyridinium ions with an alkylamine. This new transformation serves as a powerful method for synthesizing aromatic primary amines from aromatic compounds without using metal catalysts and harsh chemical reagents. High chemoselectivity of the present method is demonstrated by C-H amination of aromatic compounds bearing a nitro group to give a key intermediate for the synthesis of VLA-4 antagonist.

ALKYNYL SUBSTITUTED PYRIMIDINYL-PYRROLES ACTIVE AS KINASES INHIBITORS

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Page/Page column 45-46, (2013/03/26)

The present invention relates to alkynyl substituted pyrimidinyl-pyrrole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Jak and/or Src fa

The Kinetics of the Reactions of Picryl Chloride with Some Substituted Anilines. Part 6. 4-Substituted and 3,4-Disubstituted Anilines

Emokpae, Thomas A.,Eguavoen, Osa,Khalil-Ur-Rahman,Hirst, Jack

, p. 832 - 834 (2007/10/02)

Arrhenius parameters have been measured for the reactions of picryl chloride with the following substituted anilines in acetonitrile: 4-X- (X = F, Cl, Br, I, Me, or OMe); 3,4-X2- (X = Cl, Br, Me, or OMe); 4-X-3-nitro- (X = F, Cl, or Me); 3-X-4-methoxy- (X = F, Cl, Br, or I); 3-fluoro-4-nitro-; and 3,4,5-trimethoxy-aniline.In the 3,4-disubstituted series the effect of two methyl groups on the free energy of activation is strictly additive, but for the rest the measured rate constants are greater than those calculated on the assumption of additivity.The results are rationalized in terms of the positions of the transition state on the reaction co-ordinate.

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