74591-96-1

Upstream product

• 7743-29-5 [3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propyl]-triphenyl-phosphonium bromide 
• 123-11-5 4-methoxy-benzaldehyde 
• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 

Downstream Products

• 771426-11-0 (Z)-4-(4-methoxyphenyl)but-3-enylamine 
• 428453-39-8 N-(4-toluenesulfony)-(Z)-4-(4methoxyphenyl)but-3-enylamine 
• 84812-13-5 2-[(E)-4-(4-Methoxy-phenyl)-but-3-enyl]-isoindole-1,3-dione 
• 74592-02-2 (Z)-4-(4-Methoxy-phenyl)-but-3-enylamine; hydrochloride 

Relevant academic research and scientific papers

Bronsted acid-catalyzed intramolecular hydroamination of protected alkenylamines. Synthesis of pyrrolidines and piperidines.

[reaction: see text]. The cyclization of aminoalkenes bearing an electron-withdrawing group on the nitrogen atom was catalyzed by triflic or sulfuric acid in toluene. Pyrrolidines and piperidines were formed in excellent yields. N-phenylanilides also underwent cyclization to form gamma-lactams.